Reference : Effects of intravenous infusions of sodium bicarbonate on blood oxygen binding in cal...
Scientific journals : Article
Life sciences : Veterinary medicine & animal health
http://hdl.handle.net/2268/19708
Effects of intravenous infusions of sodium bicarbonate on blood oxygen binding in calves with diarrhoea
English
Cambier, Carole mailto [Université de Liège - ULg > Département de sciences fonctionnelles > Département de sciences fonctionnelles >]
Clerbaux, Thierry [Cliniques Universitaires Saint-Luc > Department of Internal Medicine, Division of Pneumology > > >]
Detry, Bruno [Cliniques Universitaires Saint-Luc > Department of Internal Medicine, Division of Pneumology > > >]
Marville, V. [Université de Liège - ULG > > > > > >]
Frans, A. [> > > >]
Gustin, Pascal mailto [Université de Liège - ULg > Département de sciences fonctionnelles > Pharmacologie, pharmacothérapie et toxicologie >]
2005
Veterinary Record : Journal of the British Veterinary Association
British Veterinary Assoc
156
22
706-710
Yes (verified by ORBi)
0042-4900
London
[en] blood oxygen ; calves ; diarrhoea
[en] Twelve diarrhoeic calves were treated intravenously with an isotonic solution containing sodium bicarbonate, and their oxygen equilibrium curves (OECs) were calculated under standard conditions and compared with those of a group of healthy calves. The relationships between the OECs for arterial and venous blood and the oxygen extraction ratio were investigated. in the diarrhoeic calves, the affinity of haemoglobin for oxygen, measured under standard conditions, was increased compared with the healthy animals. During the infusion, the standard partial oxygen pressure at 50 per cent saturation of haemoglobin (P50) values stayed below the values recorded in the healthy animals. At the end of the infusion the mean standard P50 of the diarrhoeic calves was lower than before the infusion. The combined effects of all the regulating factors on blood oxygen binding resulted in the OECS of the arterial and jugular venous blood of the diarrhoeic calves remaining unchanged compared with the healthy calves. However, the administration of the infusion decreased the P50 of both the arterial and venous blood to below the value recorded in the healthy calves. oxygen extraction by the tissues was impaired in the diarrhoeic calves throughout the infusion, and they remained dehydrated and depressed until 120 minutes after the infusion began
Direction Générale des Technologies de la Recherche et de l’Energie (Région Wallonne – Subsides 3012 and 2555
Researchers ; Professionals
http://hdl.handle.net/2268/19708

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