Reference : Mechanisms of HTLV-1 persistence and transformation.
Scientific journals : Article
Human health sciences : Oncology
http://hdl.handle.net/2268/19687
Mechanisms of HTLV-1 persistence and transformation.
English
Boxus, Mathieu mailto [Université de Liège - ULg > > Gembloux Agro-Bio Tech >]
Willems, Luc mailto [Université de Liège - ULg > > Gembloux Agro-Bio Tech >]
2009
British Journal of Cancer
Nature Publishing Group
101
9
1497-501
Yes (verified by ORBi)
International
0007-0920
1532-1827
London
United Kingdom
[en] Basic-Leucine Zipper Transcription Factors/physiology ; Cell Transformation, Viral ; DNA Damage ; Gene Products, rex/physiology ; Gene Products, tax/physiology ; Genomic Instability ; Human T-lymphotropic virus 1/genetics/physiology ; Humans ; Leukemia-Lymphoma, Adult T-Cell/pathology/virology ; T-Lymphocytes/pathology ; Viral Proteins/physiology ; Virus Replication
[en] Adult T-cell leukaemia (ATL) is caused by the human T-cell lymphotropic virus type 1 (HTLV-1). HTLV-1 has elaborated strategies to persist and replicate in the presence of a strong immune response. In this review, we summarise these mechanisms and their contribution to T-cell transformation and ATL development.
http://hdl.handle.net/2268/19687
10.1038/sj.bjc.6605345

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