[en] Pestiviruses are enveloped single-chain ribonucleic acid viruses with a positive polarity. Pestiviruses include the viruses of classical swine fever (hog cholera), Border disease of sheep, mucosal disease of cattle, and isolates obtained from wild animals, such as red deer (Cervus elaphus). Among ruminants, pestiviruses have developed a remarkable strategy for assuring their persistence. Through epigenetic transmission, they lead to the birth of asymptomatic carrier animals harbouring non-cytopathic variants, which become immunotolerant to the strain of virus present. The presence of a small number of asymptomatic carriers enables the virus to circulate within a herd by horizontal transmission, leading to the birth of a new generation of asymptomatic carriers.
Disciplines :
Veterinary medicine & animal health
Author, co-author :
Pastoret, Paul-Pierre ; Université de Liège - ULiège > Faculté de médecine vétérinaire > Virologie-Immunologie
Boulanger, D.; Université de Liège - ULiège > Faculté de médecine vétérinaire > Virologie-Immunologie
Mignon, Bernard ; Université de Liège - ULiège > Faculté de médecine vétérinaire > Virologie-Immunologie
Waxweiler, Sophie; Université de Liège - ULiège > Faculté de médecine vétérinaire > Virologie-Immunologie
Language :
French
Title :
Le portage asymptomatique des Pestivirus chez les ruminants
Alternative titles :
[en] Asymptomatic Carriage of Pestivirus in Ruminants
Publication date :
December 1992
Journal title :
Revue Scientifique et Technique. Office International des Epizooties
ISSN :
0253-1933
eISSN :
1608-0637
Publisher :
Office International des Epizooties (OIE), Paris, France