[en] PURPOSE: To experimentally compare the optical performance
of three types of hydrophobic intraocular lenses
(IOLs): extended depth of focus, bifocal, and trifocal.
METHODS: The tested IOLs were: TECNIS ZMB00 (bifocal;
Abbott Medical Optics, Abbott Park, IL), TECNIS
Symfony ZXR00 (extended depth of focus; Abbott Medical
Optics), and FineVision GFree hydrophobic (trifocal;
PhysIOL, Liège, Belgium). Their surface topography was
analyzed by optical microscopy. Modulation transfer
function (MTF) and spherical aberrations were determined
on optical bench for variable pupil apertures and
with two cornea models (0 μm and +0.28 μm). United
States Air Force target imaging was analyzed for different
focal points (near, intermediate, and far). Point
spread function (PSF) and halos were quantified and
compared.
RESULTS: The three lenses presented step-like optic
topography. For a pupil size of 3 mm or greater, clearly
distinctive MTF peaks were observed for all lenses:
two peaks for the extended depth of focus and bifocal
lenses with +1.75 and +4.00 diopters (D) addition,
respectively, and three peaks for the trifocal lens with
+1.75 and +3.50 addition for intermediate and near
vision, respectively. The extended depth of focus and
bifocal lens had slightly higher MTF at best focus with
the +0.28 μm cornea model than with the 0 μm model,
whereas the trifocal lens was likely to be more independent
of the corneal spherical aberrations.CONCLUSIONS: It appears that the three lenses rely on
light diffraction for their optical performance, presenting
halos with comparable intensities. For small pupil apertures
(< 3 mm), the MTF peaks for the far and intermediate
focal distances of the trifocal and extended depth
of focus lenses overlap, but the trifocal lens presented
an additional MTF peak for the near focal points.
Disciplines :
Physics
Author, co-author :
Gatinel, Damien
Loicq, Jerôme ; Université de Liège > CSL (Centre Spatial de Liège)
Language :
English
Title :
Clinically Relevant Optical Properties of Bifocal, Trifocal, and Extended Depth of Focus Intraocular Lenses
Publication date :
April 2016
Journal title :
Journal of Refractive Surgery
ISSN :
1081-597X
Publisher :
SLACK Incorporated, Thorofare, United States - New Jersey
Lang A, Portney V. Interpreting multifocal intraocular lens modulation transfer functions. J Cataract Refract Surg. 1993;19:505-512.
Pieh S, Fiala W, Malz A, Stork W. In vitro Strehl ratios with spherical, aberration-free, average, and customized spherical aberration-correcting intraocular lenses. Invest Ophthalmol Vis Sci. 2009;50:1264-1270.
Artigas JM, Menezo JL, Peris C, Felipe A, Díaz-Llopis M. Image quality with multifocal intraocular lenses and the effect of pupil size: comparison of refractive and hybrid refractive-diffractive designs. J Cataract Refract Surg. 2007;33:2111-2117.
Plaza-Puche AB, Alió JL, MacRae S, Zheleznyak L, Sala E, Yoon G. Correlating optical bench performance with clinical defocus curves in varifocal and trifocal intraocular lenses. J Refract Surg. 2015;31:300-307.
Campbell FW, Green DG. Optical and retinal factors affecting visual resolution. J Physiol. 1965;181:576-593.
Maxwell WA, Lane SS, Zhou F. Performance of presbyopiacorrecting intraocular lenses in distance optical bench tests. J Cataract Refract Surg. 2009;35:166-171.
Kim MJ, Zheleznyak L, Macrae S, Tchah H, Yoon G. Objective evaluation of through-focus optical performance of presbyopiacorrecting intraocular lenses using an optical bench system. J Cataract Refract Surg. 2011;37:1305-1312.
Gatinel D, Houbrechts Y. Comparison of bifocal and trifocal diffractive and refractive intraocular lenses using an optical bench. J Cataract Refract Surg. 2013;39:1093-1099.
Weeber HA. Multi-ring lens, systems and methods for extended depth of focus. US patent US2014168602. August 19, 2014.
Cillino S, Casuccio A, Di Pace F, et al. One-year outcomes with new-generation multifocal intraocular lenses. Ophthalmology. 2008;115:1508-1516.
Gatinel D, Pagnoulle C, Houbrechts Y, Gobin L. Design and qualification of a diffractive trifocal optical profile for intraocular lenses. J Cataract Refract Surg. 2011;37:2060-2067.
Houbrechts Y, Pagnoulle C, Gatinel D. Intraocular lens. European patent WO2011092169. August 4, 2011.
Pagnoulle C, Nolet De Brauwere Van Steeland M. Polymer composition for an intraocular lens. European patent WO2006063994. June 22, 2006.
Madrid-Costa D, Ruiz-Alcocer J, Ferrer-Blasco T, García-Lázaro S, Montés-Micó R. Optical quality differences between three multifocal intraocular lenses: bifocal low add, bifocal moderate add, and trifocal. J Refract Surg. 2013;29:749-754.
Ruiz-Alcocer J, Madrid-Costa D, García-Lázaro S, Ferrer-Blasco T, Montés-Micó R. Optical performance of two new trifocal intraocular lenses: through-focus MTF and influence of pupil size. Clin Experiment Ophthalmol. 2014;42:271-276.
Beiko GH, Haigis W, Steinmueller A. Distribution of corneal spherical aberration in a comprehensive ophthalmology practice and whether keratometry can predict aberration values. J Cataract Refract Surg. 2007;33:848-858.
Schnapf JL, Kraft TW, Baylor DA. Spectral sensitivity of human cone photoreceptors. Nature. 1987;325:439-441.
Fujikado T, Saika M. Evaluation of actual retinal images produced by misaligned aspheric intraocular lenses in a model eye. Clin Ophthalmol. 2014;28;8:2415-2423.
de Vries NE, Webers CA, Montés-Micó R, Ferrer-Blasco T, Nuijts RM. Visual outcomes after cataract surgery with implantation of a +3.00 D or +4.00 D aspheric diffractive multifocal intraocular lens: Comparative study. J Cataract Refract Surg. 2010;36:1316-1322.
Gundersen KG, Potvin R. Comparative visual performance with monofocal and multifocal intraocular lenses. Clin Ophthalmol. 2013;7:1979-1985.