Article (Scientific journals)
Combinaison fixe atorvastatine-ezetimibe (Atozet(R)).
Scheen, André
2016In Revue Médicale de Liège, 71 (1), p. 47-52
Peer reviewed
 

Files


Full Text
201601_10.pdf
Publisher postprint (577.3 kB)
Download

All documents in ORBi are protected by a user license.

Send to



Details



Keywords :
Hydroxymethylglutaryl-CoA Reductase Inhibitors/administration & dosage/therapeutic use; Hypercholesterolemia/complications/drug therapy; Risk Factors
Abstract :
[en] Cardiovascular prevention in subjects at high or very high risk requires a drastic reduction in LDL cholesterol according to the concept "the lower, the better". The combination of an inhibitor of cholesterol synthesis and a selective inhibitor of intestinal absorption results in a complementary and synergistic LDL-lowering activity. Besides a first fixed combination ezetimibe-simvastatin (Inegy(R)), a new fixed combination is presented, Atozet(R) that combines atorvastatin and ezetimibe. Because atorvastatin is more potent than simvastatin, this novel fixed combination should facilitate reaching therapeutic goals in terms of LDL cholesterol amongst patients with severe hypercholesterolaemia and/or at high or very high cardiovascular risk.
Disciplines :
Endocrinology, metabolism & nutrition
Pharmacy, pharmacology & toxicology
Author, co-author :
Scheen, André  ;  Université de Liège > Département des sciences cliniques > Diabétologie, nutrition et maladie métaboliques
Language :
French
Title :
Combinaison fixe atorvastatine-ezetimibe (Atozet(R)).
Alternative titles :
[en] FIXED COMBINATION ATORVASTATIN-EZETIMIBE (ATOZET(R))
Publication date :
2016
Journal title :
Revue Médicale de Liège
ISSN :
0370-629X
eISSN :
2566-1566
Publisher :
Université de Liège. Revue Médicale de Liège, Liège, Belgium
Volume :
71
Issue :
1
Pages :
47-52
Peer reviewed :
Peer reviewed
Additional URL :
Available on ORBi :
since 07 April 2016

Statistics


Number of views
345 (6 by ULiège)
Number of downloads
1810 (2 by ULiège)

Scopus citations®
 
2
Scopus citations®
without self-citations
1

Bibliography


Similar publications



Contact ORBi