Article (Scientific journals)
From Near-Infrared and Raman to Surface-Enhanced Raman Spectroscopy: Progress, Limitations, Perspectives in Bioanalysis
Dumont, Elodie; De Bleye, Charlotte; Sacre, Pierre-Yves et al.
2016In Bioanalysis, 8 (10), p. 1077-1103
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Keywords :
Vibrational spectroscopy; Near-Infrared spectroscopy; Raman scattering; Surface-enhanced Raman scattering (SERS); Immunoassays; Quantitative bioanalysis; Chemometrics; Surface functionalization; Label-free SERS; Extrinsic SERS
Abstract :
[en] Over recent decades, spreading environmental concern entailed the expansion of green chemistry analytical tools. Vibrational spectroscopy, belonging to this class of analytical tool, is particularly interesting taking into account its numerous advantages such as fast data acquisition and no sample preparation. In this context, Near-Infrared, Raman and mainly Surface-Enhanced Raman Spectroscopy (SERS) have thus gained interest in many fields including bioanalysis. The two former techniques only ensure the analysis of concentrated compounds in simple matrices, whereas the emergence of SERS improved the performances of vibrational spectroscopy to very sensitive and selective analyses. Complex SERS substrates were also developed enabling biomarker measurements, paving the way for SERS immunoassays. Therefore, in this paper, the strengths and weaknesses of these techniques will be highlighted with a focus on recent progress.
Research center :
Centre Interfacultaire de Recherche du Médicament - CIRM
Disciplines :
Pharmacy, pharmacology & toxicology
Author, co-author :
Dumont, Elodie ;  Université de Liège > Département de pharmacie > Chimie analytique
De Bleye, Charlotte  ;  Université de Liège > Département de pharmacie > Chimie analytique
Sacre, Pierre-Yves  ;  Université de Liège > Département de pharmacie > Chimie analytique
Netchacovitch, Lauranne ;  Université de Liège > Département de pharmacie > Chimie analytique
Hubert, Philippe  ;  Université de Liège > Département de pharmacie > Chimie analytique
Ziemons, Eric  ;  Université de Liège > Département de pharmacie > Département de pharmacie
Language :
English
Title :
From Near-Infrared and Raman to Surface-Enhanced Raman Spectroscopy: Progress, Limitations, Perspectives in Bioanalysis
Alternative titles :
[fr] De la spectroscopie Proche Infrarouge et Raman à la diffusion Raman exaltée de surface : Progrès, limitations, perspectives en bioanalyse
Publication date :
15 April 2016
Journal title :
Bioanalysis
ISSN :
1757-6180
eISSN :
1757-6199
Publisher :
Future Science, London, United Kingdom
Volume :
8
Issue :
10
Pages :
1077-1103
Peer reviewed :
Peer Reviewed verified by ORBi
Funders :
F.R.S.-FNRS - Fonds de la Recherche Scientifique [BE]
Région wallonne [BE]
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since 05 April 2016

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