Clostridium difficile infection and intestinal microbiota interactions

[en] Clostridium difficile remains the leading cause of healthcare-associated diarrhoea and outbreaks continue to occur worldwide. Aside from nosocomial C. difficile infection, the bacterium is also increasingly important as a community pathogen. Furthermore, asymptomatic carriage of C. difficile in neonates, adults and animals is also well recognised. The investigation of the gut's microbial communities, in both healthy subjects and patients suffering C. difficile infection (CDI), provides findings and information relevant for developing new successful approaches for its treatment, such as faecal microbiota transplantation, or for the prophylaxis of the infection by modification of the gut microbiota using functional foods and beverages. The analysis of all available data shows new insights into the role of intestinal microbiota in health and disease.

Disciplines :

Microbiology

Author, co-author :

Rodriguez Diaz, Cristina ; Université de Liège > Département de sciences des denrées alimentaires (DDA) > Technologie des denrées alimentaires

Taminiau, Bernard ; Université de Liège > Département de sciences des denrées alimentaires (DDA) > Microbiologie des denrées alimentaires

Van Broeck, Johan; Université Catholique de Louvain > Belgian Reference Centre for Clostridium difficile > Pole de Microbiologie Medicale

Michel, Delmée; Université Catholique de Louvain - UCL > Belgian Reference Centre for Clostridium difficile > Pôle de Microbiologie Medicale

Daube, Georges ; Université de Liège > Département de sciences des denrées alimentaires (DDA) > Microbiologie des denrées alimentaires

Language :

English

Title :

Clostridium difficile infection and intestinal microbiota interactions

Publication date :

2015

Journal title :

Microbial Pathogenesis

ISSN :

0882-4010

eISSN :

1096-1208

Publisher :

Academic Press, London, United Kingdom

Volume :

Pages :

201-209

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 23 March 2016

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