Article (Scientific journals)
Development of specific antibodies mediating antibody-dependent cell-mediated cytotoxicity following experimental infection of cattle with bovine herpesvirus 1 and subsequent viral reactivation.
Hanton, G.; Thiry, Etienne; Brochier, B. et al.
1986In Veterinary Microbiology, 11 (1-2), p. 51-9
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Keywords :
Animals; Antibodies, Viral/immunology; Antibody Formation; Antibody-Dependent Cell Cytotoxicity; Cattle; Complement System Proteins/immunology; Cytotoxicity, Immunologic; Dexamethasone/pharmacology; Herpesviridae/drug effects/growth & development/immunology; Herpesviridae Infections/immunology; Male; Neutrophils/immunology; Time Factors; Virus Activation
Abstract :
[en] Evolution of sensitizing antibodies involved in antibody-dependent cell-mediated cytotoxicity (ADCC), antibody-complement cell lysis and complement-facilitated ADCC was followed in bulls after primary infection by a wild strain of infectious bovine rhinotracheitis virus (bovine herpesvirus 1; BHV-1) and after experimental reactivation of the virus. These antibodies were detected between the 4th and the 7th day after primary infection, reached a maximum level after 2 weeks and rose slightly after reactivation of the virus following dexamethasone treatment. The presence of endogenous complement slightly enhanced the ADCC reaction.
Disciplines :
Veterinary medicine & animal health
Microbiology
Author, co-author :
Hanton, G.
Thiry, Etienne ;  Université de Liège - ULiège > Département des maladies infectieuses et parasitaires > Virologie, épidémiologie et pathologie des maladies virales
Brochier, B.
Derboven, G.
Pastoret, Paul-Pierre ;  Université de Liège - ULiège > Département des maladies infectieuses et parasitaires > Département des maladies infectieuses et parasitaires
Language :
English
Title :
Development of specific antibodies mediating antibody-dependent cell-mediated cytotoxicity following experimental infection of cattle with bovine herpesvirus 1 and subsequent viral reactivation.
Publication date :
1986
Journal title :
Veterinary Microbiology
ISSN :
0378-1135
eISSN :
1873-2542
Publisher :
Elsevier Science, Amsterdam, Netherlands
Volume :
11
Issue :
1-2
Pages :
51-9
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 21 August 2009

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