Schwartz DA, Loftus EV Jr, Tremaine WJ, et al. The natural history of fistulizing Crohn s disease in Olmsted County, Minnesota. Gastroenterology 2002;122:875 80.
Eglinton TW, Barclay ML, Gearry RB, et al. The spectrum of perianal Crohn s disease in a population-based cohort. Dis Colon Rectum 2012;55:773 7.
Norton C, Dibley LB, Bassett P. Faecal incontinence in inflammatory bowel disease: Associations and effect on quality of life. J Crohns Colitis 2013;7:e302 11.
Mueller MH, Geis M, Glatzle J, et al. Risk of fecal diversion in complicated perianal Crohn s disease. J Gastrointest Surg 2007;11:529 37.
Michelassi F, Melis M, Rubin M, et al. Surgical treatment of anorectal complications in Crohn s disease. Surgery 2000;128:597 603.
Thia KT, Mahadevan U, Feagan BG, et al. Ciprofloxacin or metronidazole for the treatment of perianal fistulas in patients with Crohn s disease: A randomized, double-blind, placebo-controlled pilot study. Inflamm Bowel Dis 2009;15:17 24.
Pearson DC, May GR, Fick GH, et al. Azathioprine and 6-mercaptopurine in Crohn disease. A meta-Analysis. Ann Intern Med 1995;123:132 42.
Hanauer SB, Smith MB. Rapid closure of Crohn s disease fistulas with continuous intravenous cyclosporin A. Am J Gastroenterol 1993;88:646 9.
Sandborn WJ, Present DH, Isaacs KL, et al. Tacrolimus for the treatment of fistulas in patients with Crohn s disease: A randomized, placebo-controlled trial. Gastroenterology 2003;125:380 8.
Plamondon S, Ng SC, Kamm MA. Thalidomide in luminal and fistulizing Crohn s disease resistant to standard therapies. Aliment Pharmacol Ther 2007;25:557 67.
Sands BE, Anderson FH, Bernstein CN, et al. Infliximab maintenance therapy for fistulizing Crohn s disease. N Engl J Med 2004;350:876 85.
Present DH, Rutgeerts P, Targan S, et al. Infliximab for the treatment of fistulas in patients with Crohn s disease. N Engl J Med 1999;340:1398 405.
Dignass A, Van Assche G, Lindsay JO, et al. The second European evidence-based Consensus on the diagnosis and management of Crohn s disease: Current management. J Crohns C olitis 2010;4:28 62.
Colombel JF, Schwartz DA, Sandborn WJ, et al. Adalimumab for the treatment of fistulas in patients with Crohn s disease. Gut 2009;58:940 8.
Van Assche G, Vanbeckevoort D, Bielen D, et al. Magnetic resonance imaging of the effects of infliximab on perianal fistulizing Crohn s disease. Am J Gastroenterol 2003;98:332 9.
Soltani A, Kaiser AM. Endorectal advancement flap for cryptoglandular or Crohn s fistula-in-Ano. Dis Colon Rectum 2010;53:486 95.
Furst A, Schmidbauer C, Swol-Ben J, et al. Gracilis transposition for repair of recurrent anovaginal and rectovaginal fistulas in Crohn s disease. Int J Colorectal Dis 2008;23:349 53.
Madbouly KM, El Shazly W, Abbas KS, et al. Ligation of intersphincteric fistula tract versus mucosal advancement flap in patients with high transsphincteric fistula-in-Ano: A prospective randomized trial. Dis Colon Rectum 2014;57:1202 8.
Grimaud JC, Munoz-Bongrand N, Siproudhis L, et al. Fibrin glue is effective healing perianal fistulas in patients with Crohn s disease. Gastroenterology 2010;138:2275 81, 2281 e1.
Badylak S, Kokini K, Tullius B, et al. Morphologic study of small intestinal submucosa as a body wall repair device. J Surg Res 2002;103:190 202.
Champagne BJ, O Connor LM, Ferguson M, et al. Efficacy of anal fistula plug in closure of cryptoglandular fistulas: long-Term follow-up. Dis Colon Rectum 2006;49:1817 21.
O Connor L, Champagne BJ, Ferguson MA, et al. Efficacy of anal fistula plug in closure of Crohn s anorectal fistulas. Dis Colon Rectum 2006;49:1569 73.
Irvine EJ. Usual therapy improves perianal Crohn s disease as measured by a new disease activity index. McMaster IBD Study Group. J Clin Gastroenterol 1995;20:27 32.
Irvine EJ, Feagan B, Rochon J, et al. Quality of life: A valid and reliable measure of therapeutic efficacy in the treatment of inflammatory bowel disease. Canadian Crohn s Relapse Prevention Trial Study Group. Gastroenterology 1994;106:287 96.
Ellis CN. Bioprosthetic plugs for complex anal fistulas: An early experience. J Surg Educ 2007;64:36 40.
Safar B, Jobanputra S, Sands D, et al. Anal fistula plug: initial experience and outcomes. Dis Colon Rectum 2009;52:248 52.
Schwandner T, Roblick MH, Kierer W, et al. Surgical treatment of complex anal fistulas with the anal fistula plug: A prospective, multicenter study. Dis Colon Rectum 2009;52:1578 83.
Ellis CN. Outcomes with the use of bioprosthetic grafts to reinforce the ligation of the intersphincteric fistula tract [BioLIFT procedure] for the management of complex anal fistulas. Dis Colon Rectum 2010;53:1361 4.
Johnson EK, Gaw JU, Armstrong DN. Efficacy of anal fistula plug vs. fibrin glue in closure of anorectal fistulas. Dis Colon Rectum 2006;49:371 6.
Christoforidis D, Pieh MC, Madoff RD, et al. Treatment of transsphincteric anal fistulas by endorectal advancement flap or collagen fistula plug: A comparative study. Dis Colon Rectum 2009;52:18 22.
McGee MF, Champagne BJ, Stulberg JJ, et al. Tract length predicts successful closure with anal fistula plug in cryptoglandular fistulas. Dis Colon Rectum 2010;53:1116 20.
Garg P, Song J, Bhatia A, et al. The efficacy of anal fistula plug in fistula-inano: A systematic review. Colorectal Dis 2010;12:965 70.
Lawes DA, Efron JE, Abbas M, et al. Early experience with the bioabsorbable anal fistula plug. World J Surg 2008;32:1157 9.
Chung W, Kazemi P, Ko D, et al. Anal fistula plug and fibrin glue versus conventional treatment in repair of complex anal fistulas. Am J Surg 2009;197:604 8.
Wang JY, Garcia-Aguilar J, Sternberg JA, et al. Treatment of transsphincteric anal fistulas: Are fistula plugs an acceptable alternative? Dis Colon Rectum 2009;52:692 7.
Zubaidi A, Al-Obeed O. Anal fistula plug in high fistula-in-Ano: An early Saudi experience. Dis Colon Rectum 2009;52:1584 8.
Adamina M, Ross T, Guenin MO, et al. Anal fistula plug: A prospective evaluation of success, continence and quality of life in the treatment of complex fistulae. Colorectal Dis 2014;16:547 54.
O Riordan JM, Datta I, Johnston C, et al. A systematic review of the anal fistula plug for patients with Crohn s and non-Crohn s related fistula-inano. Dis Colon Rectum 2012;55:351 8.
Ortiz H, Marzo J, Ciga MA, et al. Randomized clinical trial of anal fistula plug versus endorectal advancement flap for the treatment of high cryptoglandular fistula in ano. Br J Surg 2009;96:608 12.
van Koperen PJ, Bemelman WA, Gerhards MF, et al. The anal fistula plug treatment compared with the mucosal advancement flap for cryptoglandular high transsphincteric perianal fistula: A double-blinded multicenter randomized trial. Dis Colon Rectum 2011;54:387 93.
The Surgisis AFP anal fistula plug: report of a consensus conference. Colorectal Dis 2008;10:17 20.
O Riordan JM, Datta I, Johnston C, et al. A systematic review of the anal fistula plug for patients with Crohn s and non-Crohn s related fistula-inano. Dis Colon Rectum 2012;55:351 8.
de la Portilla F, Alba F, Garcia-Olmo D, et al. Expanded allogeneic adipose-derived stem cells [eASCs] for the treatment of complex perianal fistula in Crohn s disease: results from a multicenter phase I/IIa clinical trial. Int J Colorectal Dis 2013;28:313 23.
Lee WY, Park KJ, Cho YB, et al. Autologous adipose tissue-derived stem cells treatment demonstrated favorable and sustainable therapeutic effect for Crohn s fistula. Stem Cells 2013;31:2575 81.
Gingold DS, Murrell ZA, Fleshner PR. A prospective evaluation of the ligation of the intersphincteric tract procedure for complex anal fistula in patients with Crohn disease. Ann Surg 2014;260:1057 61.