Reference : Usefulness of 18fdg Positron Emission Tomography in Detection and Follow-up of Digest...
Scientific journals : Article
Human health sciences : Oncology
Usefulness of 18fdg Positron Emission Tomography in Detection and Follow-up of Digestive Cancers
Paulus, P. [> > > >]
Hustinx, Roland mailto [Université de Liège - ULg > Département des sciences cliniques > Médecine nucléaire]
Daenen, Frédéric [Centre Hospitalier Universitaire de Liège - CHU > > Médecine nucléaire >]
Comhair, Nicole [Centre Hospitalier Universitaire de Liège - CHU > > Administration des patients - Expédition >]
Rigo, Pierre mailto [Université de Liège - ULg > Département des sciences de la motricité > Pathologie générale et médecine nucléaire >]
Acta Gastro-Enterologica Belgica
4, Oct-Dec
Yes (verified by ORBi)
[en] FDG ; Positron emission tomography ; colorectal cancer
[fr] pancreatic cancer ; Liver metastases
[en] PET is a diagnostic method that creates high resolution, 3 dimensional tomographic images of the distribution of positron emitting radionuclides in the human body. Recent technological developments allow the use of whole-body PET devices in clinical oncology. 18FDG is a glucose analog transported and competitively used with glucose reflecting the increased glucose metabolism into malignant cells. Differential diagnosis between chronic pancreatitis and pancreatic cancer is already a well-documented indication. For initial staging of gastro-esophageal and colorectal tumours, results are preliminary but the clinical impact seems to be rather limited. At present, the major indication of FDG-PET is the detection and staging of colorectal cancer recurrences. FDG-PET allows the differentiation between scared tissue and tumour when structural imaging is often confusing. In the same time, the whole-body imaging capability provides unique information that can modify loco-regional and liver staging. Overall, FDG-PET affects the clinical management of 30 to 40% of these patients. Quantitative assessment of therapeutic response to chemotherapy regimen appears to be one of the most promising applications of FDG-PET. Since the most effective therapy of colorectal cancer are often surgical, the role of chemotherapy in colorectal cancer remains limited to adjuvant therapy and in advanced disease. However, FDG-PET could be of great value in assessing the response of oesophageal carcinomas to chemo-radio therapy, before surgery. In our experience, FDG-PET appears to be the first line diagnostic method in the detection and staging of colorectal recurrence and differential diagnosis of pancreatic tumour versus chronic pancreatitis.

File(s) associated to this reference

Fulltext file(s):

Restricted access
Paulus P et al, Acta Gastro Ent Belg 1997.pdfPublisher postprint310.49 kBRequest copy

Bookmark and Share SFX Query

All documents in ORBi are protected by a user license.