Reference : Whole-Body 18fdg Positron Emission Tomography in the Staging of Non-Small Cell Lung Cancer
Scientific journals : Article
Human health sciences : Oncology
Human health sciences : Radiology, nuclear medicine & imaging
http://hdl.handle.net/2268/19122
Whole-Body 18fdg Positron Emission Tomography in the Staging of Non-Small Cell Lung Cancer
English
Bury, Thierry mailto [Université de Liège - ULg > Département des sciences de la motricité > Physiologie humaine et physiologie de l'effort physique]
Dowlati, A. [> > > >]
Paulus, Patrick [> > > >]
Corhay, Jean-Louis mailto [Université de Liège - ULg > Département des sciences cliniques > Département des sciences cliniques >]
Hustinx, Roland mailto [Université de Liège - ULg > Département des sciences cliniques > Médecine nucléaire]
Ghaye, Benoît [Centre Hospitalier Universitaire de Liège - CHU > > Imagerie médicale >]
Radermecker, Maurice mailto [Université de Liège - ULg > Services généraux (Faculté de médecine) > Relations académiques et scientifiques (Médecine) >]
Rigo, Pierre mailto [Université de Liège - ULg > Département des sciences de la motricité > Pathologie générale et médecine nucléaire >]
Nov-1997
European Respiratory Journal
10
11
2529-34
Yes (verified by ORBi)
International
0903-1936
[en] Non-small cell lung cancer ; Positron emission tomography ; Presurgical staging
[en] Despite advances in morphological imaging, some patients with lung cancer are found to have nonresectable disease at surgery or die of recurrence within yr of surgery. We performed a prospective study in 109 patients to compare the accuracy of whole-body positron emission tomography (PET) using fluorine-18 deoxyglucose (18FDG) and conventional imaging (CI) methods for the staging of non-small cell lung cancer (NSCLC). When CI or PET study suggested metastatic disease, confirmation was obtained by biopsy or follow-up information. As compared to CI, 18FDG-PET correctly changed the N stage in 22 patients (33%) and the M stage in 15 patients (14%). For the detection of distant metastases, PET study showed five false-positive sites and no false-negative cases. Currently, the accuracy of PET in the detection of M stage is 96%. Our study shows that visual interpretation of whole-body fluorine-18 deoxyglucose-positron emission tomography images can improve the diagnostic accuracy in the staging of non-small cell lung cancer. Further experience is needed to establish if metabolic imaging would be a cost-effective tool in the future management of lung cancer.
http://hdl.handle.net/2268/19122

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