Article (Scientific journals)
Molecular characterization of the bovine GHRL gene
Colinet, Frédéric; Portetelle, Daniel; Renaville, Robert
2009In Archiv für Tierzucht, 52 (1), p. 79-84
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Keywords :
GHRL; ghrelin; cattle; polymorphism; sequence
Abstract :
[en] Bovine ghrelin, a 27 amino acid pepticle, has been identified in oxyntic glands of the abomasum. It is an endogenous ligand for growth hormone secretagogue receptor and stimulates food intake and growth hormone secretion. The bovine GHRL gene was completely sequenced and consists of five exons and four introns. Like mouse and human GHRL genes, we found that the bovine GHRL gene also contains a first non-coding exon of 21 bp. The bovine GHRL gene codes for 116 amino acid pepticle named preproghrelin which contains the ghrelin pepticle and another pepticle similar to obestatin. Sequence analysis revealed eight polymorphisms, which are located in the non-coding sequence of the gene.
Disciplines :
Animal production & animal husbandry
Genetics & genetic processes
Author, co-author :
Colinet, Frédéric ;  Faculté Universitaire des Sciences Agronomiques de Gembloux - FUSAGx > Biologie animale et microbienne
Portetelle, Daniel ;  Université de Liège - ULiège > Chimie et bio-industries > Biologie animale et microbienne
Renaville, Robert ;  Université de Liège - ULiège > Chimie et bio-industries > Biologie animale et microbienne
Language :
English
Title :
Molecular characterization of the bovine GHRL gene
Publication date :
2009
Journal title :
Archiv für Tierzucht
ISSN :
0003-9438
eISSN :
2363-9822
Publisher :
Akademie Verlag, Dummerstorf, Germany
Volume :
52
Issue :
1
Pages :
79-84
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 17 August 2009

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