Article (Scientific journals)
Genetic and evolutionary perspectives on genogroup III, genotype 2 bovine noroviruses
Mauroy, Axel; Scipioni, Alexandra; Mathijs, Elisabeth et al.
2013In Archives of Virology, 159 (1), p. 39-49
Peer Reviewed verified by ORBi
 

Files


Full Text
genetic evolution BoNoV.pdf
Publisher postprint (531.26 kB)
Request a copy

All documents in ORBi are protected by a user license.

Send to



Details



Abstract :
[en] Bovine noroviruses are enteric pathogens that are detected in stool samples from cattle. Five genogroups are currently described in the genus Norovirus (family Caliciviridae), and within the genogroups, sequences are further divided into genotypes according to genetic homology and phylogenetic relationships. In this study, stool specimens from Belgian cattle were screened by RT-PCR. All of the sequences that were detected were phylogenetically related to genogroup III genotype 2 bovine noroviruses, confirming their higher prevalence in comparison with strains from genotype 1. When other sequences from around the world were introduced, phylogenetic inferences allowed neither the determination of phylogenetic lineages over time nor the deduction of topotypes for genotype 2 bovine noroviruses. Three complete genotype 2 bovine norovirus sequences were also compared genetically (Newbury2/1976 /UK, Dumfries/1994/UK and B309/2003/BE). Interestingly, the genetic divergence of the complete genomes of these three strains was relatively low, but a region of the N-terminal protein encoded by ORF1, the hypervariable region of the capsid gene encoded by ORF2, and a region of the minor structural protein encoded by ORF3 seem to be the most exposed to genetic evolution. Bayesian inference also showed that genetic evolution of genogroup III, genotype 2 bovine noroviruses over a 30-year period seemed to be lower than that already reported for noroviruses from the genotypes 3 and 4 in genogroup II.
Disciplines :
Veterinary medicine & animal health
Author, co-author :
Mauroy, Axel ;  Université de Liège - ULiège > Département des maladies infectieuses et parasitaires > Virologie vétérinaire et maladies virales animales
Scipioni, Alexandra ;  Université de Liège - ULiège
Mathijs, Elisabeth 
Ziant, Dominique ;  Université de Liège - ULiège
Daube, Georges  ;  Université de Liège - ULiège > Département de sciences des denrées alimentaires > Microbiologie des denrées alimentaires
Thiry, Etienne ;  Université de Liège - ULiège > Département des maladies infectieuses et parasitaires > Virologie vétérinaire et maladies virales animales
Language :
English
Title :
Genetic and evolutionary perspectives on genogroup III, genotype 2 bovine noroviruses
Publication date :
24 July 2013
Journal title :
Archives of Virology
ISSN :
0304-8608
eISSN :
1432-8798
Publisher :
Springer Science & Business Media B.V.
Volume :
159
Issue :
1
Pages :
39-49
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 15 November 2013

Statistics


Number of views
63 (11 by ULiège)
Number of downloads
0 (0 by ULiège)

Scopus citations®
 
9
Scopus citations®
without self-citations
4
OpenCitations
 
9

Bibliography


Similar publications



Contact ORBi