Article (Scientific journals)
Dawn simulation light: a potential cardiac events protector.
Viola, Antoine U.; Gabel, Virginie; Chellappa, Sarah Laxhmi et al.
2015In Sleep Medicine, 16 (4), p. 457-61
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Keywords :
Cardiac control; Circadian functions; Heart rate; Heart rate variability; Light
Abstract :
[en] OBJECTIVE/BACKGROUND: Major cardiovascular events frequently increase in the morning due to abrupt changes in the sympatho-vagal cardiac control during the transition from sleep to wakefulness. These neural changes are translated into stepwise increases in cardiac functions, resulting in a potential cardiovascular stress. Here, we explored whether light can "optimize" heart rate and its neural control, by actively promoting a less steep transition from sleep to wakefulness, thus minimizing morning cardiovascular vulnerability. METHODS: Seventeen healthy young men were awakened 2-hours before their habitual wake-time. In a counterbalanced within-subject design, we applied a control condition (darkness during sleep and dim light during wakefulness) or dawn-simulation-light (DSL) starting 30-minutes before and ending 30-minutes after scheduled wake-up time. RESULTS: Our data reveal a significantly gradient reduction in heart rate during the transition from sleep to wakefulness, when applying DSL as compared to a control condition. Likewise, cardiac sympatho-vagal control smoothly increased throughout the 30-min sleep episode preceding scheduled wake-up under DSL and remained stable for the first 30-min of wakefulness. Interestingly, these effects were mostly driven by changes in the parasympathetic cardiac control. CONCLUSIONS: Our data demonstrate for the first time that a non-invasive strategy, as light exposure surrounding the wake-up process, can significantly reduce the deleterious sleep-to-wake evoked cardiac modulation in healthy young men awakened under conditions of increased sleep pressure. A translational approach of this light exposure, which closely resembles natural lighting conditions in the morning, may therefore act as a potential protector for cardiac vulnerability in the critical morning hours.
Disciplines :
Neurosciences & behavior
Author, co-author :
Viola, Antoine U.
Gabel, Virginie
Chellappa, Sarah Laxhmi ;  Université de Liège > Centre de recherches du cyclotron
Schmidt, Christina  ;  Université de Liège > Département de Psychologie : cognition et comportement > Neuropsychologie
Hommes, Vanja
Tobaldini, Eleonora
Montano, Nicola
Cajochen, Christian
Language :
English
Title :
Dawn simulation light: a potential cardiac events protector.
Publication date :
2015
Journal title :
Sleep Medicine
ISSN :
1389-9457
eISSN :
1878-5506
Publisher :
Elsevier, Netherlands
Volume :
16
Issue :
4
Pages :
457-61
Peer reviewed :
Peer Reviewed verified by ORBi
Commentary :
Copyright (c) 2014 Elsevier B.V. All rights reserved.
Available on ORBi :
since 26 October 2015

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