Article (Scientific journals)
Inflammatory markers and cardiometabolic diseases.
ESSER, Nathalie; Paquot, Nicolas; Scheen, André
2015In Acta Clinica Belgica, 70 (3), p. 193-9
Peer Reviewed verified by ORBi
 

Files


Full Text
2015 Inflammatory markers Esser Acta Clinica Belgica Feb 2015.pdf
Author preprint (562.76 kB)
Download

All documents in ORBi are protected by a user license.

Send to



Details



Keywords :
C-reactive protein,; Cardiovascular disease,; Inflammation,; Insulin resistance,; Type 2 diabetes mellitus
Abstract :
[en] OBJECTIVES: A growing body of evidence emerges that obesity, metabolic syndrome, type 2 diabetes and cardiovascular disease are intimately related to chronic inflammation. METHODS: A narrative review summarizing the most recent data of the literature describing the pathological implications of inflammation in obese patients with cardiometabolic disorders. RESULTS: Besides high-sensitive C-reactive protein, various circulating or in situ inflammatory markers have been identified, presumably reflecting the presence of inflammation in various key-organs (visceral adipose tissue, skeletal muscle, pancreatic islets, liver, intestine, arterial wall). Available data support the concept that targeting inflammation, not only reduces systemic inflammatory markers, but also improves insulin sensitivity and ameliorates glucose control in insulin-resistant patients, thus potentially reducing the risk of cardiovascular complications. CONCLUSION: These observations confirm the role of inflammation in cardiometabolic diseases and support the development of pharmacological strategies that aim at reducing inflammation, especially in patients with type 2 diabetes.
Disciplines :
Cardiovascular & respiratory systems
Endocrinology, metabolism & nutrition
Author, co-author :
ESSER, Nathalie  
Paquot, Nicolas ;  Université de Liège > Département des sciences de la santé publique > Nutrition
Scheen, André  ;  Université de Liège > Département des sciences cliniques > Diabétologie, nutrition et maladie métaboliques
Language :
English
Title :
Inflammatory markers and cardiometabolic diseases.
Publication date :
2015
Journal title :
Acta Clinica Belgica
ISSN :
1784-3286
eISSN :
2295-3337
Publisher :
Taylor and Francis, Abingdon, United Kingdom
Volume :
70
Issue :
3
Pages :
193-9
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 25 October 2015

Statistics


Number of views
310 (15 by ULiège)
Number of downloads
975 (3 by ULiège)

Scopus citations®
 
54
Scopus citations®
without self-citations
52
OpenCitations
 
43

Bibliography


Similar publications



Contact ORBi