Reference : Preparation and evaluation of liposomes encapsulating synthetic MMP inhibitor (Ro 28-...
Scientific congresses and symposiums : Paper published in a journal
Human health sciences : Pharmacy, pharmacology & toxicology
Physical, chemical, mathematical & earth Sciences : Chemistry
http://hdl.handle.net/2268/18665
Preparation and evaluation of liposomes encapsulating synthetic MMP inhibitor (Ro 28-2653) - cyclodextrin complexes
English
Piette, Marie mailto [Université de Liège - ULg > Département de pharmacie > Pharmacie galénique >]
Castagne, Delphine mailto [Université de Liège - ULg > Département de pharmacie > Pharmacie galénique et magistrale >]
Delattre, Luc mailto [Université de Liège - ULg > Département de pharmacie > Département de pharmacie >]
Piel, Géraldine mailto [Université de Liège - ULg > Département de pharmacie > Pharmacie galénique et magistrale >]
Apr-2007
Journal of Inclusion Phenomena and Macrocyclic Chemistry
Springer
57
1-4
101-103
Yes (verified by ORBi)
International
0923-0750
Dordrecht
[en] matrix metalloproteinase inhibitor ; Ro 28-2653 ; liposome ; cyclodextrin ; release kinetics
[en] In this study, preparation and evaluation of liposomes, intended for intravenous administration, encapsulating synthetic MMP inhibitor (Ro 28-2653) - cyclodextrin complexes were realized. An increase in Ro solubility, via formation of binary (Ro/HP beta CD) or ternary (Ro/HP beta CD/L-lysine) complexes, permitted a similar increase in encapsulation efficiency of liposomes (Table 1). Moreover, Ro release kinetics depend on the encapsulation efficiency.
Researchers ; Professionals
http://hdl.handle.net/2268/18665

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