Poster (Scientific congresses and symposiums)
Modelling of the Nonlinear End-Systolic Pressure-Volume Relation and Volume-at-Zero-Pressure in Porcine Experiments
Davidson, Shaun M.; Kannangara, D. Oliver; Pretty, Christopher G. et al.
201537th International Conference of the IEEE Engineering in Medicine and Biology Society
 

Files


Full Text
ESPVR Poster v1.pdf
Publisher postprint (2.37 MB)
Download

All documents in ORBi are protected by a user license.

Send to



Details



Abstract :
[en] The End-Systolic Pressure-Volume Relation (ESPVR) is generally modelled as a linear relationship between P and V as cardiac reflexes, such as the baroreflex, are typically suppressed in experiments. However, ESPVR has been observed to behave in a curvilinear fashion when cardiac reflexes are not supressed, suggesting the curvilinear function may be more clinically appropriate. Data was gathered from 41 vena cava occlusion manoeuvres performed experimentally at a variety of PEEPs across 6 porcine specimens, and ESPVR determined for each pig. An exponential model of ESPVR was found to provide a higher correlation coefficient than a linear model in 6 out of 7 cases, and a lower Akaike Information Criterion (AIC) value in all cases. Further, the exponential ESPVR provided positive V0 values in a physiological range in6 out of 7 cases analysed, while the linear ESPVR produced positive V0 values in only 3 out of 7 cases, suggesting linear extrapolation of ESPVR to determine V0 may be flawed.
Disciplines :
Engineering, computing & technology: Multidisciplinary, general & others
Cardiovascular & respiratory systems
Author, co-author :
Davidson, Shaun M.
Kannangara, D. Oliver
Pretty, Christopher G.
Kamoi, Shun
Pironet, Antoine ;  Université de Liège > Département d'astrophys., géophysique et océanographie (AGO) > Thermodynamique des phénomènes irréversibles
Desaive, Thomas  ;  Université de Liège > Département d'astrophys., géophysique et océanographie (AGO) > Thermodynamique des phénomènes irréversibles
Chase, J. Geoffrey
Language :
English
Title :
Modelling of the Nonlinear End-Systolic Pressure-Volume Relation and Volume-at-Zero-Pressure in Porcine Experiments
Publication date :
August 2015
Event name :
37th International Conference of the IEEE Engineering in Medicine and Biology Society
Event organizer :
IEEE Engineering in Medicine and Biology Society
Event place :
Milan, Italy
Event date :
du 25 au 29 août 2015
Audience :
International
Available on ORBi :
since 07 September 2015

Statistics


Number of views
68 (3 by ULiège)
Number of downloads
211 (0 by ULiège)

Bibliography


Similar publications



Contact ORBi