[en] Enzyme kinetics, amino acid and nucleotide sequencing, oligonucleotide-directed mutagenesis, protein crystallography and X-ray diffraction, computer molecular graphics and theoretical chemistry contribute much to the unravelling of the mechanisms of enzyme catalysis. The present paper summarizes our state of knowledge concerning several peculiar bacterial enzymes, namely the active-site serine and active-site Zn++ DD-peptidases and β-lactamases.
Disciplines :
Biochemistry, biophysics & molecular biology
Author, co-author :
Ghuysen, Jean-Marie ; Université de Liège - ULiège > Institut de Chimie > Service de Microbiologie
Language :
English
Title :
The D-alanyl-D-alanine-cleaving peptidases and β-lactamases. Structure and mechanism
Publication date :
1987
Main work title :
Perspectives in Biotechnology
Editor :
Cardoso Duarte, José M.
Archer, L. J.
Bull, A. T.
Holt, G.
Publisher :
Springer
ISBN/EAN :
978-1-4612-9049-0 978-1-4613-1883-5
Collection name :
NATO ASI Series, vol. 128, Series A: Life Sciences
