Balthazart, Jacques ; Université de Liège > Département des sciences biomédicales et précliniques > Département des sciences biomédicales et précliniques
Young, Larry J.; Emory University > Department of Psychiatry and Behavioral Sciences > Center for Translational Social Neuroscience
Language :
English
Title :
Mate selection, Sexual orientation and Pair bonding
Adkins-Regan E. Hormones and animal social behavior 2005, Princeton University Press, Princeton (NJ).
Fisher R.A. The genetical theory of natural selection 1930, Clarendon Press, Oxford.
Moller A.P., Jennions M.D. How important are direct fitness benefits of sexual selection?. Naturwissenschaften 2001, 88:401-415.
Kokko H., Brooks R., Jennions M.D., Morley J. The evolution of mate choice and mating biases. Proc Biol Sci 2003, 270:653-664.
Darwin C. The descent of man and selection in relation to sex 1871, John Murray, London.
Insel T.R., Young L.J. Neuropeptides and the evolution of social behavior. Curr Opin Neurobiol 2000, 10:784-789.
Birkhead T.R., Moller A.P. Extra-pair copulation and extra-pair paternity in birds. Anim Behav 1995, 49:843-848.
Kleiman D. Monogamy in mammals. Q Rev Biol 1977, 52:39-69.
Getz L.L., Carter C.S. Prairie-vole partnerships. Am Sci 1996, 84:56-62.
White D.R., Betzig L., Borgerhoff Mulder M., et al. Rethinking polygyny: co-wives, code and cultural systems. Curr Anthropol 1988, 29:529.
Henrich J., Boyd R., Richerson P.J. The puzzle of monogamous marriage. Philos Trans R Soc Lond B Biol Sci 2012, 367:657-669.
Brennan P.A., Kendrick K.M. Mammalian social odours: attraction and individual recognition. Philos Trans R Soc Lond B Biol Sci 2006, 361:2061-2078.
Domjan M.P. The principles of learning and behavior 2002, Wadsworth Publishing, Belmont (CA).
Domjan M. Adult learning and mate choice: possibilities and experimental evidence. Am Zool 1992, 32:48-61.
Lorenz K. Der Kumpan in der Umwelt des Vogels. J Ornithol 1935, 83:137-213.
Hinde R.A. Animal behaviour 1970, McGraw-Hill, New York. 2nd ed.
Immelman K. Sexual and other long-term aspects of imprinting in birds and other species. Adv Study Behav 1972, 4:147-174.
ten Cate C. Behavioral development: toward understanding processes. Perspectives in ethology 1989, vol. 8. Cambridge Univ. Press, New York. P.P.G. Bateson, P.H. Klopfer (Eds.).
Kendrick K.M., Hinton M.R., Atkins K., Haupt M.A., Skinner J.D. Mothers determine sexual preferences. Nature 1998, 395:229-230.
Kendrick K.M., Haupt M.A., Hinton M.R., Broad K.D., Skinner J.D. Sex differences in the influence of mothers on the sociosexual preferences of their offspring. Horm Behav 2001, 40:322-338.
Lorenz K. The evolution of behavior. Sci Am 1958, 199:67-83.
Kaltenhäuser D. Uber Evolutionsvorgänge in der Schwimmentenbalz. Z Tierpsychol 1971, 29:481-540.
Johnson K.P., McKinney F., Wilson R., Sorenson M.D. The evolution of postcopulatory displays in dabbling ducks (Anatini): a phylogenetic perspective. Anim Behav 2000, 59:953-963.
Fujita K. Development of visual preference for closely related species by infant and juvenile macaques with restricted social experience. Primates 1993, 34:141-150.
Reiner A., Perkel D.J., Bruce L.L., et al. Revised nomenclature for avian telencephalon and some related brainstem nuclei. J Comp Neurol 2004, 473:377-414.
Margoliash D. Functional organization of forebrain pathways for song production and perception. J Neurobiol 1997, 33:671-693.
Theunissen F.E., Doupe A.J. Temporal and spectral sensitivity of complex auditory neurons in the nucleus HVc of male zebra finches. J Neurosci 1998, 18:3786-3802.
Krebs J., Ashcroft R., Webber M. Song repertoires and territory defence in the great tit. Nature 1978, 271:539-542.
Goodson J.L., Adkins-Regan E. Playback of crow of male Japanese quail elicits female phonotaxis. Condor 1999, 99:990-993.
Barfield R.J., Geyer L.A. Sexual behavior: ultrasonic postejaculatory song of the male rat. Science 1972, 176:1349-1350.
Portfors C.V. Types and functions of ultrasonic vocalizations in laboratory rats and mice. J Am Assoc Lab Anim Sci 2007, 46:28-34.
Nyby J., Whitney G. Experience affects behavioral responses to sex odors. Chemical signals 1979, 173-192. Plenum Press, New York. D. Muller-Schwarze, R.M. Silverstein (Eds.).
Mainardi D., Marsan M., Pasquali A. Causation of sexual preferences of the house mouse. The behaviour of mice reared by parents whose odour was artificially altered. Atti Soc Ital Sci Nat Mus Civ Stor Nat Milano 1965, 104:325-338.
Alleva A., D'Udine B., Oliverio A. Effect d'une expérience olfactive précoce sur les préférences sexuelles de deux souches de souris consanguines. Biol Behav 1981, 6:73-78.
Quadagno D.M., Banks E.M. The effect of reciprocal cross fostering on the behavior of two species of rodents. Mus musculus and Baiomys taylori ater. Anim Behav 1970, 18:379-390.
Murphy M.R. Sexual preferences of male hamsters: importance of preweaning and adult experience, vaginal secretion and olfactory or vomeronasal sensation. Behav Neural Biol 1980, 30:323-340.
Muller-Schwarze D., Muller-Schwarze C. Olfactory imprinting in a precocial mammal. Nature 1971, 229:55-56.
Cheal M. Social olfaction: a review of the ontogeny of olfactory influences on vertebrate behavior. Behav Biol 1975, 15:1-25.
Vandenbergh J.G. Pheromones and mammalian reproduction. Knobil and Neill's physiology of reproduction 2006, 2041-2058. Elsevier, Amsterdam. 3rd ed. J.D. Neil (Ed.).
McCarthy M.M., De Vries G.J., Forger N.G. Sexual differentiation of the brain: mode, mechanisms, and meaning. Hormones, brain and behavior 2009, 1707-1746. Academic Press, San Diego (CA). D.W. Pfaff, A.P. Arnold, A.M. Etgen, S.E. Fahrbach, R.T. Rubin (Eds.).
LeVay S. Gay, straight, and the reason why. The science of sexual orientation 2010, Oxford University Press, New York.
Balthazart J. The biology of homosexuality 2011, Oxford University Press, New York.
Beach F.A. Hormones and behavior 1948, Paul B. Hoeber, Inc., New York.
Balthazart J., Arnold A.P., Adkins-Regan E. Sexual differentiation of brain and behavior in birds. Hormones, brain and behavior 2009, 1745-1787. Academic Press, San Diego (CA). D.W. Pfaff, A.P. Arnold, A.M. Etgen, S.E. Fahrbach, R.T. Rubin (Eds.).
Phoenix C.H., Goy R.W., Gerall A.A., Young W.C. Organizational action of prenatally administered testosterone propionate on the tissues mediating behavior in the female guinea pig. Endocrinology 1959, 65:369-382.
Goy R.W., McEwen B.S. Sexual differentiation of the brain 1980, The MIT Press, Cambridge (MA).
Arnold A.P., Breedlove S.M. Organizational and activational effects of sex steroids on brain and behavior: a reanalysis. Horm Behav 1985, 19:469-498.
McCarthy M.M. Sexual differentiation of brain and behavior. Handbook of neuroendocrinology 2012, 393-413. Academic Press, San Diego. G. Fink, D.W. Pfaff, J. Levine (Eds.).
Bakker J., De Mees C., Douhard Q., et al. Alpha-fetoprotein protects the developing female mouse brain from masculinization and defeminization by estrogens. Nat Neurosci 2006, 9:220-226.
Brock O., Baum M.J., Bakker J. The development of female sexual behavior requires prepubertal estradiol. J Neurosci 2011, 31:5574-5578.
Meyer-Bahlburg H.F. Psychoendocrine research on sexual orientation. Current status and future options. Prog Brain Res 1984, 61:375-398.
Bakker J., Van Ophemert J., Slob A.K. Organization of partner preference and sexual behavior and its nocturnal rhythmicity in male rats. Behav Neurosci 1993, 107:1049-1058.
Bakker J., Van Ophemert J., Slob A.K. Sexual differentiation of odor and partner preference in the rat. Physiol Behav 1996, 60:489-494.
Clemens L.G. The aromatization hypothesis 1970-1990. Brain aromatase, estrogens and behavior 2012, 135-168. Oxford University Press, New York. J. Balthazart, G.F. Ball (Eds.).
Södersten P. A historical and personal perspective on the aromatization revolution: Steinach confirmed. Brain aromatase, estrogens and behavior 2012, 281-314. Oxford University Press, New York. J. Balthazart, G.F. Ball (Eds.).
Bakker J., Baum M.J., Slob A.K. Neonatal inhibition of brain estrogen synthesis alters adult neural Fos responses to mating and pheromonal stimulation in the male rat. Neuroscience 1996, 74:251-260.
Henley C.L., Nunez A.A., Clemens L.G. Estrogen treatment during development alters adult partner preference and reproductive behavior in female laboratory rats. Horm Behav 2009, 55:68-75.
Bodo C., Rissman E.F. Androgen receptor is essential for sexual differentiation of responses to olfactory cues in mice. Eur J Neurosci 2007, 25:2182-2190.
Bakker J., Honda S., Harada N., Balthazart J. Sexual partner preference requires a functional aromatase (cyp19) gene in male mice. Horm Behav 2002, 42:158-171.
Brock O., Bakker J. Potential contribution of prenatal estrogens to the sexual differentiation of mate preferences in mice. Horm Behav 2011, 59:83-89.
Tobet S.A., Fox T.O. Sex differences in neuronal morphology influenced hormonally throughout life. Handbook of behavioral neurobiology. Sexual differentiation 1992, vol 11:41-83. Plenum Press, New York. A.A. Gerall, H. Moltz, I.L. Ward (Eds.).
Allen L.S., Hines M., Shryne J.E., Gorski R.A. Two sexually dimorphic cell groups in the human brain. J Neurosci 1989, 9:497-506.
Tobet S.A., Zahniser D.J., Baum M.J. Sexual dimorphism in the preoptic/anterior hypothalamic area of ferrets: effects of adult exposure to sex steroids. Brain Res 1986, 364:249-257.
Paredes R.G., Baum M.J. Altered sexual partner preference in male ferrets given excitotoxic lesions of the preoptic area anterior hypothalamus. J Neurosci 1995, 15:6619-6630.
Paredes R.G., Tzschentke T., Nakach N. Lesions of the medial preoptic area anterior hypothalamus (MPOA/AH) modify partner preference in male rats. Brain Res 1998, 813:1-8.
Gorski R.A., Gordon J.H., Shryne J.E., Southam A.M. Evidence for a morphological sex difference within the medial preoptic area of the rat brain. Brain Res 1978, 148:333-346.
Jacobson C.D., Csernus V.J., Shryne J.E., Gorski R.A. The influence of gonadectomy, androgen exposure, or a gonadal graft in the neonatal rat on the volume of the sexually dimorphic nucleus of the preoptic area. J Neurosci 1981, 1:1142-1147.
Houtsmuller E.J., Brand T., de Jonge F.H., Joosten R.N., van de Poll N.E., Slob A.K. SDN-POA volume, sexual behavior, and partner preference of male rats affected by perinatal treatment with ATD. Physiol Behav 1994, 56:535-541.
Bagemihl B. Biological exuberance. Animal homosexuality and natural diversity 1999, St Martin's Press, New York.
Poianni A. Animal homosexuality. A biological perspective 2010, Cambridge University Press, Cambridge (UK).
Roselli C.E., Reddy R.C., Kaufman K.R. The development of male-oriented behavior in rams. Front Neuroendocrinol 2011, 32:164-169.
Roselli C.E., Larkin K., Resko J.A., Stellflug J.N., Stormshak F. The volume of a sexually dimorphic nucleus in the ovine medial preoptic area/anterior hypothalamus varies with sexual partner preference. Endocrinology 2004, 145:478-483.
Perkins A., Roselli C.E. The ram as a model for behavioral neuroendocrinology. Horm Behav 2007, 52:70-77.
Roselli C.E., Stadelman H., Reeve R., Bishop C.V., Stormshak F. The ovine sexually dimorphic nucleus of the medial preoptic area is organized prenatally by testosterone. Endocrinology 2007, 148:4450-4457.
Hines M. Brain gender 2004, Oxford University Press, Oxford.
Baron-Cohen S. The essential difference: men, women and the extreme male brain 2004, Penguin Press Science, London.
Baron-Cohen S. Prenatal testosterone in mind 2006, MIT Press, Cambridge (MA).
Hines M. Prenatal endocrine influences on sexual orientation and on sexually differentiated childhood behavior. Front Neuroendocrinol 2011, 32:170-182.
Ball G.F., Balthazart J. Individual variation and the endocrine regulation of behaviour and physiology in birds: a cellular/molecular perspective. Philos Trans R Soc Lond B Biol Sci 2008, 363:1699-1710.
Tetel M.J., Auger A.P., Charlier T.D. Who's in charge? Nuclear receptor coactivator and corepressor function in brain and behavior. Front Neuroendocrinol 2009, 30:328-342.
Rice W.R., Friberg U., Gavrilets S. Homosexuality as a consequence of epigenetically canalized sexual development. Q Rev Biol 2012, 87:343-368.
Hines M. Sex steroids and human behavior: prenatal androgen exposure and sex-typical play behavior in children. Ann N Y Acad Sci 2003, 1007:272-282.
MacLaughlin D.T., Donahoe P.K. Sex determination and differentiation. N Engl J Med 2004, 350:367-378.
Berenbaum S.A., Hines M. Early androgens are related to childhood sex-typed toy preferences. Psychol Sci 1992, 3:203-206.
Hines M., Kaufman F.R. Androgen and the development of human sex-typical behavior: rough-and-tumble play and sex of preferred playmates in children with congenital adrenal hyperplasia (CAH). Child Dev 1994, 65:1042-1053.
Berenbaum S.A., Snyder E. Early hormonal influences on childhood sex-typed activity and playmate preferences: implications for the development of sexual orientation. Dev Psychol 1995, 31:31-42.
Beltz A.M., Swanson J.L., Berenbaum S.A. Gendered occupational interests: prenatal androgen effects on psychological orientation to things versus people. Horm Behav 2011, 60:313-317.
Money J., Schwartz M., Lewis V.G. Adult erotosexual status and fetal hormonal masculinization and demasculinization: 46, XX congenital virilizing adrenal hyperplasia and 46, XY androgen-insensitivity syndrome compared. Psychoneuroendocrinology 1984, 9:405-414.
Dittmann R.W., Kappes M.E., Kappes M.H. Sexual behavior in adolescent and adult females with congenital adrenal hyperplasia. Psychoneuroendocrinology 1992, 17:153-170.
Zucker K.J., Bradley S.J., Oliver G., Blake J., Fleming S., Hood J. Psychosexual development of women with congenital adrenal hyperplasia. Horm Behav 1996, 30:300-318.
Hines M. Prenatal testosterone and gender-related behaviour. Eur J Endocrinol 2006, 155:S115-S121.
Meyer-Bahlburg H.F. Male gender identity in an XX individual with congenital adrenal hyperplasia. J Sex Med 2009, 6:297-298.
Meyer-Bahlburg H.F., Dolezal C., Baker S.W., New M.I. Sexual orientation in women with classical or non-classical congenital adrenal hyperplasia as a function of degree of prenatal androgen excess. Arch Sex Behav 2008, 37:85-99.
Ehrhardt A.A., Meyer-Bahlburg H.F., Rosen L.R., et al. Sexual orientation after prenatal exposure to exogenous estrogen. Arch Sex Behav 1985, 14:57-77.
Meyer-Bahlburg H.F., Ehrhardt A.A., Rosen L.R. Prenatal estrogens and the development of homosexual orientation. Dev Psychol 1995, s31:12-21.
Swaab D.F. Sexual differentiation of the brain and behavior. Best Pract Res Clin Endocrinol Metab 2007, 21:431-444.
Titus-Ernstoff L., Perez K., Hatch E.E., et al. Psychosexual characteristics of men and women exposed prenatally to diethylstilbestrol. Epidemiology 2003, 14:155-160.
Reiner W.G., Gearhart J.P. Discordant sexual identity in some genetic males with cloacal exstrophy assigned to female sex at birth. N Engl J Med 2004, 350:333-341.
Reiner W.G. Psychosexual development in genetic males assigned female: the cloacal exstrophy experience. Child Adolesc Psychiatr Clin N Am 2004, 13:657-674. ix.
Meyer-Bahlburg H.F. Gender identity outcome in female-raised 46, XY persons with penile agenesis, cloacal exstrophy of the bladder, or penile ablation. Arch Sex Behav 2005, 34:423-438.
Imperato-McGinley J. 5 alpha-reductase deficiency: human and animal models. Eur Urol 1994, 25:20-23.
Imperato-McGinley J., Zhu Y.S. Androgens and male physiology the syndrome of 5alpha-reductase-2 deficiency. Mol Cell Endocrinol 2002, 198:51-59.
Imperato-McGinley J., Miller M., Wilson J.D., Peterson R.E., Shackleton C., Gajdusek D.C. A cluster of male pseudohermaphrodites with 5 alpha-reductase deficiency in Papua New Guinea. Clin Endocrinol (Oxf) 1991, 34:293-298.
Rahman Q., Wilson G.D. Born gay? The psychobiology of human sexual orientation. Pers Individ Dif 2003, 34:1337-1382.
Savic I., Berglund H., Lindstrom P. Brain response to putative pheromones in homosexual men. Proc Natl Acad Sci USA 2005, 102:7356-7361.
Berglund H., Lindstrom P., Savic I. Brain response to putative pheromones in lesbian women. Proc Natl Acad Sci USA 2006, 103:8269-8274.
Balthazart J. Brain development and sexual orientation 2012, Morgan & Claypool Life Sciences, Charleston (SC).
Brown W.M., Finn C.J., Breedlove S.M. Sexual dimorphism in digit-length ratios of laboratory mice. Anat Rec 2002, 267:231-234.
Romano M., Rubolini D., Martinelli R., Bonisoli Alquati A., Saino N. Experimental manipulation of yolk testosterone affects digit length ratios in the ring-necked pheasant (Phasianus colchicus). Horm Behav 2005, 48:342-346.
Lutchmaya S., Baron-Cohen S., Raggatt P., Knickmeyer R., Manning J.T. 2nd to 4th digit ratios, fetal testosterone and estradiol. Early Hum Dev 2004, 77:23-28.
Manning J.T., Fink B., Neave N., Szwed A. The second to fourth digit ratio and asymmetry. Ann Hum Biol 2006, 33:480-492.
Brown W.M., Finn C.J., Cooke B.M., Breedlove S.M. Differences in finger length ratios between self-identified "butch" and "femme" lesbians. Arch Sex Behav 2002, 31:123-127.
Brown W.M., Hines M., Fane B.A., Breedlove S.M. Masculinized finger length patterns in human males and females with congenital adrenal hyperplasia. Horm Behav 2002, 42:380-386.
Berenbaum S.A., Bryk K.K., Nowak N., Quigley C.A., Moffat S. Fingers as a marker of prenatal androgen exposure. Endocrinology 2009, 150:5119-5124.
Breedlove S.M. Minireview: organizational hypothesis: instances of the fingerpost. Endocrinology 2010, 151:4116-4122.
Williams T.J., Pepitone M.E., Christensen S.E., et al. Finger-length ratios and sexual orientation. Nature 2000, 404:455-456.
McFadden D., Shubel E. Relative lengths of fingers and toes in human males and females. Horm Behav 2002, 42:492-500.
Rahman Q., Wilson G.D. Sexual orientation and the 2nd to 4th finger length ratio: evidence for organising effects of sex hormones or developmental instability?. Psychoneuroendocrinology 2003, 28:288-303.
Kraemer B., Noll T., Delsignore A., Milos G., Schnyder U., Hepp U. Finger length ratio (2D:4D) and dimensions of sexual orientation. Neuropsychobiology 2006, 53:210-214.
Lippa R.A. Are 2D:4D finger-length ratios related to sexual orientation? Yes for men, no for women. J Pers Soc Psychol 2003, 85:179-188.
Wallen K. Does finger fat produce sex differences in second to fourth digit ratios?. Endocrinology 2009, 150:4819-4822.
Martin J.T., Nguyen D.H. Anthropometric analysis of homosexuals and heterosexuals: implications for early hormone exposure. Horm Behav 2004, 45:31-39.
McFadden D. Masculinization effects in the auditory system. Arch Sex Behav 2002, 31:99-111.
McFadden D., Pasanen E.G., Valero M.D., Roberts E.K., Lee T.M. Effect of prenatal androgens on click-evoked otoacoustic emissions in male and female sheep (Ovis aries). Horm Behav 2009, 55:98-105.
McFadden D., Pasanen E.G. Comparison of the auditory systems of heterosexuals and homosexuals: click-evoked otoacoustic emissions. Proc Natl Acad Sci USA 1998, 95:2709-2713.
McFadden D. What do sex, twins, spotted hyenas, ADHD, and sexual orientation have in common?. Perspect Psychol Sci 2008, 3:309-323.
McFadden D., Champlin C.A. Comparison of auditory evoked potentials in heterosexual, homosexual, and bisexual males and females. J Assoc Res Otolaryngol 2000, 1:89-99.
Rahman Q., Kumari V., Wilson G.D. Sexual orientation-related differences in prepulse inhibition of the human startle response. Behav Neurosci 2003, 117:1096-1102.
Dörner G. Zur frage einer neuroendocrinen pathogenese, prophylaxe und therapie angeborenen sexualdeviationen. Dtsch Med Wochenschr 1969, 94:390-396.
Dörner G. Sexualhormonabhängige Gehirndifferenzierung und Sexualität 1972, Springer, Berlin, Heidelberg (New York).
Dörner G. Hormones and brain differentiation 1976, Elsevier, Amsterdam (Oxford, New York).
Dörner G. Sexual differentiation of the brain. Vitamins and hormones 1980, Academic Press, Inc., New York, p. 325-81.
Baum M.J., Carroll R.S., Erskine M.S., Tobet S.A. Neuroendocrine response to estrogen and sexual orientation. Science 1985, 230:960-961.
Gladue B.A., Green R., Hellman R.E. Neuroendocrine response to estrogen and sexual orientation. Science 1984, 225:1496-1499.
Karsch F.J., Dierschke D.J., Knobil E. Sexual differentiation of pituitary function: apparent difference between primates and rodents. Science 1973, 179:484-486.
Feder H.H. Perinatal hormones and their role in the development of sexually dimorphic behaviors. Neuroendocrinology of reproduction 1981, 127-158. Plenum Press, New York. N. Adler (Ed.).
Gladue B.A. Neuroendocrine response to estrogen and sexual orientation. Science 1985, 230:961.
Swaab D.F., Hofman M.A. An enlarged suprachiasmatic nucleus in homosexual men. Brain Res 1990, 537:141-148.
Allen L.S., Gorski R.A. Sexual orientation and the size of the anterior commissure in the human brain. Proc Natl Acad Sci USA 1992, 89:7199-7202.
LeVay S. A difference in hypothalamic structure between heterosexual and homosexual men. Science 1991, 253:1034-1037.
Byne W., Tobet S., Mattiace L.A., et al. The interstitial nuclei of the human anterior hypothalamus: an investigation of variation with sex, sexual orientation, and HIV status. Horm Behav 2001, 40:86-92.
Garcia-Falgueras A., Swaab D.F. A sex difference in the hypothalamic uncinate nucleus: relationship to gender identity. Brain 2008, 131:3132-3146.
Arnold A.P., Gorski R.A. Gonadal steroid induction of structural sex differences in the central nervous system. Ann Rev Neurosci 1984, 7:413-442.
Rhees R.W., Shryne J.E., Gorski R.A. Termination of the hormone-sensitive period for differentiation of the sexually dimorphic nucleus of the preoptic area in male and female rats. Dev Brain Res 1990, 52:17-23.
Roselli C.E., Larkin K., Schrunk J.M., Stormshak F. Sexual partner preference, hypothalamic morphology and aromatase in rams. Physiol Behav 2004, 83:233-245.
Ward I.L., Ward O.B. Sexual behavior differentiation: effects of prenatal manipulations in rats. Handbook of behavioral neurobiology. Reproduction 1985, vol. 7:77-98. Plenum Press, New York. N. Adler, D. Pfaff, R.W. Goy (Eds.).
Anderson D.K., Rhees R.W., Fleming D.E. Effects of prenatal stress on differentiation of the sexually dimorphic nucleus of the preoptic area (SDN-POA) of the rat brain. Brain Res 1985, 332:113-118.
Kerchner M., Ward I.L. SDN-MPOA volume in male rats is decreased by prenatal stress, but is not related to ejaculatory behavior. Brain Res 1992, 581:244-251.
Dorner G., Geier T., Ahrens L., et al. Prenatal stress as possible aetiogenetic factor of homosexuality in human males. Endokrinologie 1980, 75:365-368.
Dorner G., Schenk B., Schmiedel B., Ahrens L. Stressful events in prenatal life of bi- and homosexual men. Exp Clin Endocrinol 1983, 81:83-87.
Schmidt G., Clement U. Does peace prevent homosexuality?. Arch Sex Behav 1990, 19:183-187.
Bailey J.M., Willerman L., Parks C. A test of the maternal stress theory of human male homosexuality. Arch Sex Behav 1991, 20:277-293.
Ellis L., Ames M.A., Peckham W., Ahrens L. Sexual orientation of human offspring may be altered by severe maternal stress during pregnancy. J Sex Res 1988, 25:152-157.
Amateau S.K., McCarthy M.M. Induction of PGE2 by estradiol mediates developmental masculinization of sex behavior. Nat Neurosci 2004, 7:643-650.
McCarthy M.M. How it's made: organisational effects of hormones on the developing brain. J Neuroendocrinol 2010, 22:736-742.
Bos C.L., Richel D.J., Ritsema T., Peppelenbosch M.P., Versteeg H.H. Prostanoids and prostanoid receptors in signal transduction. Int J Biochem Cell Biol 2004, 36:1187-1205.
Panzica G.C., Viglietti-Panzica C., Mura E., et al. Effects of xenoestrogens on the differentiation of behaviorally-relevant neural circuits. Front Neuroendocrinol 2007, 28:179-200.
Li A.A., Baum M.J., McIntosh L.J., Day M., Liu F., Gray L.E. Building a scientific framework for studying hormonal effects on behavior and on the development of the sexually dimorphic nervous system. Neurotoxicology 2008, 29:504-519.
Gore A.C., Patisaul H.B. Neuroendocrine disruption: historical roots, current progress, questions for the future. Front Neuroendocrinol 2010, 31:395-399.
Diamond M. Some genetic considerations in the development of sexual orientation. The development of sex differences and similarities in behavior 1993, 291-309. Kluwer Academic Publishers, Dordrecht. M. Haug, R.E. Whalen, C. Aron, K.L. Olsen (Eds.).
Bailey J.M., Pillard R.C. A genetic study of male sexual orientation. Arch Gen Psychiatry 1991, 48:1089-1096.
Bailey J.M., Dunne M.P., Martin N.G. Genetic and environmental influences on sexual orientation and its correlates in an Australian twin sample. J Pers Soc Psychol 2000, 78:524-536.
Kendler K.S., Thornton L.M., Gilman S.E., Kessler R.C. Sexual orientation in a U.S. national sample of twin and nontwin sibling pairs. Am J Psychiatry 2000, 157:1843-1846.
Kirk K.M., Bailey J.M., Dunne M.P., Martin N.G. Measurement models for sexual orientation in a community twin sample. Behav Genet 2000, 30:345-356.
LeVay S., Hamer D.H. Evidence for a biological influence in male homosexuality. Sci Am 1994, 270:44-49.
Macke J.P., Hu N., Hu S., et al. Sequence variation in the androgen receptor gene is not a common determinant of male sexual orientation. Am J Hum Genet 1993, 53:844-852.
Kruijver F.P.M., Fernández-Guasti A., Fodor M., Kraan E.M., Swaab D.F. Sex differences in androgen receptors of the human mamillary bodies are related to endocrine status rather than to sexual orientation or transsexuality. J Clin Endocrinol Metab 2001, 86:818-827.
Jost A., Vigier B., Prepin J., Perchellet J.P. Studies on sex differentiation in mammals. Recent Prog Horm Res 1973, 29:1-41.
Pask A., Renfree M.B. Sex determining genes and sexual differentiation in a marsupial. J Exp Zool 2001, 290:586-596.
Wade J., Arnold A.P. Sexual differentiation of the zebra finch song system. Ann N Y Acad Sci 2004, 1016:540-559.
Arnold A.P., Chen X. What does the "four core genotypes" mouse model tell us about sex differences in the brain and other tissues?. Front Neuroendocrinol 2009, 30:1-9.
Arnold A.P. The end of gonad-centric sex determination in mammals. Trends Genet 2012, 28:55-61.
McCarthy M.M., Arnold A.P. Reframing sexual differentiation of the brain. Nat Neurosci 2011, 14:677-683.
Hamer D.H., Hu S., Magnuson V.L., Hu N., Pattatucci A.M.L. A linkage between DNA markers on the X chromosome and male sexual orientation. Science 1993, 261:321-327.
Hu S., Pattatucci A.M., Patterson C., et al. Linkage between sexual orientation and chromosome Xq28 in males but not in females. Nat Genet 1995, 11:248-256.
Sanders A.R., Dawood K. Nature encyclopedia of life sciences 2003, Nature Publishing Group, London.
Rice G., Anderson C., Risch N., Ebers G. Male homosexuality: absence of linkage to microsatellite markers at Xq28. Science 1999, 284:665-667.
Bocklandt S., Vilain E. Sex differences in brain and behavior: hormones versus genes. Adv Genet 2007, 59:245-266.
Ngun T.C., Ghahramani N., Sanchez F.J., Bocklandt S., Vilain E. The genetics of sex differences in brain and behavior. Front Neuroendocrinol 2011, 32:227-246.
Bocklandt S., Horvath S., Vilain E., Hamer D.H. Extreme skewing of X chromosome inactivation in mothers of homosexual men. Hum Genet 2006, 118:691-694.
Mustanski B.S., Dupree M.G., Nievergelt C.M., Bocklandt S., Schork N.J., Hamer D.H. A genomewide scan of male sexual orientation. Hum Genet 2005, 116:272-278.
Dewing P., Shi T., Horvath S., Vilain E. Sexually dimorphic gene expression in mouse brain precedes gonadal differentiation. Mol Brain Res 2003, 118:82-90.
Bermejo-Alvarez P., Rizos D., Rath D., Lonergan P., Gutierrez-Adan A. Sex determines the expression level of one third of the actively expressed genes in bovine blastocysts. Proc Natl Acad Sci USA 2010, 107:3394-3399.
Bermejo-Alvarez P., Rizos D., Lonergan P., Gutierrez-Adan A. Transcriptional sexual dimorphism during preimplantation embryo development and its consequences for developmental competence and adult health and disease. Reproduction 2011, 141:563-570.
Morgan C.P., Bale T.L. Early prenatal stress epigenetically programs dysmasculinization in second-generation offspring via the paternal lineage. J Neurosci 2011, 31:11748-11755.
Blanchard R. Fraternal birth order and the maternal immune hypothesis of male homosexuality. Horm Behav 2001, 40:105-114.
Bogaert A.F., Skorska M. Sexual orientation, fraternal birth order, and the maternal immune hypothesis: a review of evidence. Front Neuroendocrinol 2011, 32:247-254.
Van Rillaer J. Les illusions de la psychanalyse 1980, Pierre Mardaga, Sprimont (Belgique).
Bénesteau J. Mensonges Freudiens 2002, Pierre Mardaga, Wavre (Belgique).
Dufresne T. Against Freud. Critics talk back 2007, Stanford University Press, Stanford (CA).
Adkins-Regan E., Ascenzi M. Social and sexual behaviour of male and female zebra finches treated with oestradiol during the nestling period. Anim Behav 1987, 35:1100-1112.
Adkins-Regan E., Yang S., Mansukhani V. Behavior of male and female zebra finches treated with an estrogen synthesis inhibitor as nestlings. Behaviour 1996, 133:847-862.
Adkins-Regan E. Testosterone increases singing and aggression but not male-typical sexual partner preference in early estrogen treated female zebra finches. Horm Behav 1999, 35:63-70.
Adkins-Regan E., Wade J. Masculinized sexual partner preference in female zebra finches with sex-reversed gonads. Horm Behav 2001, 39:22-28.
Hines M. Gender development and behavior. 6th Int symp on the biology of vertebrate sex determination (Kona, Hawaii) 2012, 1-2.
Hines M. Sexual differentiation of human brain and behavior. Abst Soc Neurosci (New Orleans) 2012, Abst 719.
Robertson G.S., Pfaus J.G., Atkinson L.J., Matsumura H., Phillips A.G., Fibiger H.C. Sexual behavior increases c-fos expression in the forebrain of the male rat. Brain Res 1991, 564:352-357.
Coolen L.M., Peters H.J.P.W., Veening J.G. Fos immunoreactivity in the rat brain following consummatory elements of sexual behavior: a sex comparison. Brain Res 1996, 738:67-82.
Savic I., Berglund H., Gulyas B., Roland P. Smelling of odorous sex hormone-like compounds causes sex-differentiated hypothalamic activations in humans. Neuron 2001, 31:661-668.
Burke S.M., Veltman D.J., Gerber J., Hummel T., Bakker J. Heterosexual men and women both show a hypothalamic response to the chemo-signal androstadienone. PloS One 2012, 7:e40993.
Clutton-Brock T., McAuliffe K. Female mate choice in mammals. Q Rev Biol 2009, 84:3-27.
MacDougall A.K., Montgomerie R. Assortative mating by carotenoid-based plumage colour: a quality indicator in American goldfinches, Carduelis tristis. Naturwissenschaften 2003, 90:464-467.
Andersson S., Ornborg J., Andersson M. Ultraviolet sexual dimorphism and assortative mating in blue tits. Proc R Soc Biol B 1998, 265:445-450.
Alcock J. Animal behavior 2005, Sinauer, Sunderland (MA).
Buchanan K.L., Catchpole C.K. Song as an indicator of male parental effort in the sedge warbler. Proc Biol Sci 2000, 267:321-326.
Sockman K.W. Neural orchestration of mate-choice plasticity in songbirds. J Ornithol 2007, 148:S225-S230.
Sockman K.W., Ball G.F. Independent effects of song quality and experience with photostimulation on expression of the immediate, early gene ZENK (EGR-1) in the auditory telencephalon of female European starlings. Dev Neurobiol 2009, 69:339-349.
Caro S.P., Sewall K.B., Salvante K.G., Sockman K.W. Female Lincoln's sparrows modulate their behavior in response to variation in male song quality. Behav Ecol 2010, 21:562-569.
Wade T.J. The relationships between symmetry and attractiveness and mating relevant decisions and behavior: a review. Symmetry 2010, 2:1081-1098.
Little A.C., Jones B.C., DeBruine L.M. Facial attractiveness: evolutionary based research. Philos Trans R Soc Lond B Biol Sci 2011, 366:1638-1659.
Johnston V.S. Mate choice decisions: the role of facial beauty. Trends Cogn Sci 2006, 10:9-13.
Zahavi A. Mate selection-a selection for a handicap. J Theor Biol 1975, 53:205-214.
Emlen D.J., Warren I.A., Johns A., Dworkin I., Lavine L.C. A mechanism of extreme growth and reliable signaling in sexually selected ornaments and weapons. Science 2012, 337:860-864.
deBruine L.M., Jones B.C., Frederick D.A., Haselton M.G., Penton-Vok I.S., Perrett D.I. Evidence for menstrual cycle shifts in women's preferences for masculinity: a response to Harris (in press) "Menstrual cycle and facial preferences reconsidered". Evol Psychol 2010, 8:768-775.
Clutton-Brock T. Sexual selection in females. Anim Behav 2009, 77:3-11.
Pfefferle D., Heistermann M., Hodges J.K., Fischer J. Male Barbary macaques eavesdrop on mating outcome: a playback study. Anim Behav 2007, 75:1885-1891.
Pipitone R.N., Gallup G.G. Women's voice attractiveness varies across the menstrual cycle. Evol Hum Behav 2008, 29:268-274.
Miller G., Tybur J., Jordan B.D. Ovulatory cycle effects on tip earnings by lap dancers: economic evidence for human estrus?. Evol Hum Behav 2007, 28:375-381.
Petit M.A., Beck T.J., Lin H.M., Bentley C., Legro R.S., Lloyd T. Femoral bone structural geometry adapts to mechanical loading and is influenced by sex steroids: the Penn State Young Women's Health Study. Bone 2004, 35:750-759.
Morris D. The naked ape 1967, Random House Inc., New York.
Young L., Alexander B. The chemistry between us: love, sex, and the science of attraction 2012, Current, New York.
Choleris E., Clipperton-Allen A.E., Phan A., Kavaliers M. Neuroendocrinology of social information processing in rats and mice. Front Neuroendocrinol 2009, 30:442-459.
Kavaliers M., Colwell D.D., Choleris E., et al. Impaired discrimination of and aversion to parasitized male odors by female oxytocin knockout mice. Genes Brain Behav 2003, 2:220-230.
Kavaliers M., Choleris E., Agmo A., et al. Inadvertent social information and the avoidance of parasitized male mice: a role for oxytocin. Proc Natl Acad Sci USA 2006, 103:4293-4298.
Kavaliers M., Choleris E. Sociality, pathogen avoidance, and the neuropeptides oxytocin and arginine vasopressin. Psychol Sci 2011, 22:1367-1374.
Hoogland J. Prairie dogs avoid extreme inbreeding. Science 1982, 215:1639-1641.
Mays H.L., Hill G.E. Choosing mates: good genes versus genes that are a good fit. Trends Ecol Evol 2004, 19:554-559.
Bateson P.P.G. Sexual imprinting and optimal outbreeding. Nature 1978, 273:659-660.
Bateson P.P.G. Preference for cousins in Japanese quail. Nature 1982, 295:236-237.
Yamazaki K., Singer A., Curan M., Beauchamp G.K. Origins, functions, and chemistry of H-2 regulated odorants. Advances in chemical signals in vertebrates 1999, 173-180. Kluwer Academic/Plenum, New York. E. Johnston, D. Muller-Schwarze, P.W. Sorensen (Eds.).
Goldstein N.I., Cagen R.H. The major histocompatibility complex and olfactory receptors. Biochemistry of taste and olfaction 1981, 93-107. Academic Press, New York. R.H. Cagen, M.R. Kare (Eds.).
Yamazaki K., Yamaguchi M., Beauchamp G.K., Bard J., Boyce E.A., Thomas L. Chemosensation: an aspect of the uniqueness of the individual. Biochemistry of taste and olfaction 1981, 85-92. Academic Press, New York. R.H. Cagen, M.R. Kare (Eds.).
Yamazaki K., Yamaguchi M., Boyse E.A., Thomas L. The major histocompatibility complex as a source of odors imparting individuality among mice. Chemical signals 1980, 267-274. Plenum Press, New York. D. uller-Schwarze, R.M. Silverstein (Eds.).
Potts W.K., Manning C.J., Wakeland E.K. Mating patterns in seminatural populations of mice influenced by MHC genotype. Nature 1991, 352:619-621.
O'Connell R.J., Singer A.G., Stem F.L., Jesmajian S., Agosta W.C. Cyclic variations in the concentration of sex attractant pheromone in hamster vaginal discharge. Behav Neural Biol 1981, 31:457-464.
Krames L., Mastromatteo L.A. Role of olfactory stimuli during copulation in male and female rats. J Comp Physiol Psychol 1973, 85:528-535.
Carr W.J., Krames L., Costonzo L.A. Previous sexual experience and olfactory preference for novel versus original sex partners in rats. J Comp Physiol Psychol 1970, 71:216-222.
Johnston R.E. Mechanisms of individual discrimination in hamsters. Chem Signals 1982, 3:245.
Curtis J.T., Liu Y., Wang Z. Lesions of the vomeronasal organ disrupt mating-induced pair bonding in female prairie voles (Microtus ochrogaster). Brain Res 2001, 901:167-174.
Williams J.R., Slotnick B.M., Kirkpatrick B.W., Carter C.S. Olfactory bulb removal affects partner preference development and estrus induction in female prairie voles. Physiol Behav 1992, 52:635-639.
Setchell J.M., Huchard E. The hidden benefits of sex: evidence for MHC-associated mate choice in primate societies. Bioessays 2010, 32:940-948.
Heymann E.W. The neglected sense of smell in primate behavior, ecology and evolution. Am J Primatol 2006, 68:514-524.
Zhang J.Z., Webb D.M. Evolutionary deterioration of the vomero-nasal pheromone transduction pathway in catarrhine primates. Proc Nat Acad Sci USA 2003, 100:8337-8341.
Keverne E.B. The vomeronasal organ. Science 1999, 286:716-720.
Keverne E.B. Importance of olfactory and vomeronasal systems for male sexual function. Physiol Behav 2004, 83:177-187.
Swaney W.T., Keverne E.B. The evolution of pheromonal communication. Behav Brain Res 2009, 200:239-247.
Thornhill R., Gangestad S.W., Miller R., Scheyd G., McCollough J.K., Franklin M. Major histocompatibility complex genes, symmetry, and body scent attractiveness in men and women. Behav Ecol 2003, 14:338-378.
Havlicek J., Roberts S.C. MHC-correlated mate choice in humans: a review. Psychoneuroendocrinology 2009, 34:497-512.
Bereczkei T., Gyuris P., Weisfeld G.E. Sexual imprinting in human mate choice. Proc Biol Sci 2004, 271:1129-1134.
Getz L.L., Carter C.S., Gavish L. The mating system of the prairie vole Microtus ochrogaster: field and laboratory evidence for pair bonding. Behav Ecol Sociobiol 1981, 8:189-194.
Getz L.L., McGuire B., Carter C.S. Social behavior, reproduction and demography of the prairie vole, Microtus ochrogaster. Ethology, Ecol Evol 2003, 15:105-118.
Carter C.S., Getz L.L., Gavish L., McDermott J.L., Arnold P. Male-related pheromones and the activation of female reproduction in the prairie vole (Microtus ochrogaster). Biol Reprod 1980, 23:1038-1045.
Ophir A.G., Phelps S.M., Sorin A.B., Wolff J.O. Social but not genetic monogamy is associated with greater breeding success in prairie voles. Anim Behav 2008, 75:1143-1154.
Burbach P., Young L.J., Russell J. Oxytocin: synthesis, secretion and reproductive functions. Knobil an Neill's physiology of reproduction 2006, 3055-3127. Elsevier, Amsterdam, NL. 3rd ed. J.D. Neill (Ed.).
Ross H.E., Cole C.D., Smith Y., et al. Characterization of the oxytocin system regulating affiliative behavior in female prairie voles. Neuroscience 2009, 162:892-903.
Ross H.E., Freeman S.M., Spiegel L.L., Ren X., Terwilliger E.F., Young L.J. Variation in oxytocin receptor density in the nucleus accumbens has differential effects on affiliative behaviors in monogamous and polygamous voles. J Neurosci 2009, 29:1312-1318.
Ross H.E., Young L.J. Oxytocin and the neural mechanisms regulating social cognition and affiliative behavior. Front Neuroendocrinol 2009, 30:534-547.
Knobloch H.S., Charlet A., Hoffmann L.C., et al. Evoked axonal oxytocin release in the central amygdala attenuates fear response. Neuron 2012, 73:553-566.
De Vries G.J. Minireview: sex differences in adult and developing brains: compensation, compensation, compensation. Endocrinology 2004, 145:1063-1068.
De Vries G., Buijs R. The origin of vasopressinergic and oxytocinergic innervation of the rat brain with special reference to the lateral septum. Brain Res 1983, 273:307-317.
Pedersen C.A., Prange A.J. Induction of maternal behavior in virgin rats after intracerebroventricular administration of oxytocin. Proc Natl Acad Sci USA 1979, 76:6661-6665.
Kendrick K.M. The neurobiology of social bonds. J Neuroendocrinol 2004, 16:1007-1008.
Kendrick K.M., Costa A.P.C.D., Broad K.D., et al. Neural control of maternal behavior and olfactory recognition of offspring. Brain Res Bull 1997, 44:383-395.
Kendrick K.M., Keverne E.B., Baldwin B.A. Intracerebroventricular oxytocin stimulates maternal behaviour in the sheep. Neuroendocrinology 1987, 46:56-61.
Williams J., Catania K., Carter C. Development of partner preferences in female prairie voles (Microtus ochrogaster): the role of social and sexual experience. Horm Behav 1992, 26:339-349.
Williams J.R., Insel T.R., Harbaugh C.R., Carter C.S. Oxytocin administered centrally facilitates formation of a partner preference in prairie voles (Microtus ochrogaster). J Neuroendocrinol 1994, 6:247-250.
Insel T.R., Hulihan T.J. A gender-specific mechanism for pair bonding: oxytocin and partner preference formation in monogamous voles. Behav Neurosci 1995, 109:782-789.
Cho M.M., DeVries A.C., Williams J.R., Carter C.S. The effects of oxytocin and vasopressin on partner preferences in male and female prairie voles (Microtus ochrogaster). Behav Neurosci 1999, 113:1071-1079.
Ahern T.H., Modi M.E., Burkett J.P., Young L.J. Evaluation of two automated metrics for analyzing partner preference tests. J Neurosci Methods 2009, 182:180-188.
Barrett CE, Young LJ. Molecular neurobiology of social bonding and social cognition. In: Canli T, editor. The Oxford handbook of molecular psychology. Oxford University Press; Online publication September 2013. doi:10.1093/oxfordhb/9780199753888.013.001.
Ferguson J.N., Aldag J.M., Insel T.R., Young L.J. Oxytocin in the medial amygdala is essential for social recognition in the mouse. J Neurosci 2001, 21:8278-8285.
Ferguson J.N., Young L.J., Hearn E.F., Matzuk M.M., Insel T.R., Winslow J.T. Social amnesia in mice lacking the oxytocin gene. Nat Genet 2000, 25:284-288.
Choleris E., Gustafsson J.A., Korach K.S., Muglia L.J., Pfaff D.W., Ogawa S. An estrogen-dependent four-gene micronet regulating social recognition: a study with oxytocin and estrogen receptor-alpha and -beta knockout mice. Proc Natl Acad Sci USA 2003, 100:6192-6197.
Insel T.R., Shapiro L.E. Oxytocin receptor distribution reflects social organization in monogamous and polygamous voles. Proc Natl Acad Sci USA 1992, 89:5981-5985.
Smeltzer M.D., Curtis J.T., Aragona B.J., Wang Z. Dopamine, oxytocin, and vasopressin receptor binding in the medial prefrontal cortex of monogamous and promiscuous voles. Neurosci Lett 2006, 394:146-151.
Young L.J., Wang Z. The neurobiology of pair bonding. Nat Neurosci 2004, 7:1048-1054.
Young L.J., Lim M.M., Gingrich B., Insel T.R. Cellular mechanisms of social attachment. Horm Behav 2001, 40:133-138.
Lim M.M., Murphy A.Z., Young L.J. Ventral striatopallidal oxytocin and vasopressin V1a receptors in the monogamous prairie vole (Microtus ochrogaster). J Comp Neurol 2004, 468:555-570.
Olazabal D.E., Young L.J. Oxytocin receptors in the nucleus accumbens facilitate "spontaneous" maternal behavior in adult female prairie voles. Neurosci 2006, 141:559-568.
Olazabal D.E., Young L.J. Species and individual differences in juvenile female alloparental care are associated with oxytocin receptor density in the striatum and the lateral septum. Horm Behav 2006, 49:681-687.
Keebaugh A.C., Young L.J. Increasing oxytocin receptor expression in the nucleus accumbens of pre-pubertal female prairie voles enhances alloparental responsiveness and partner preference formation as adults. Horm Behav 2011, 60:498-504.
Ophir A.G., Gessel A., Zheng D.J., Phelps S.M. Oxytocin receptor density is associated with male mating tactics and social monogamy. Horm Behav 2012, 61:445-453.
Ferris C.F., Albers H.E., Wesolowski S.M., Goldman B.D., Luman S.E. Vasopressin injected into the hypothalamus triggers a stereotypic behavior in golden hamsters. Science 1984, 224:521-523.
Albers H., Pollock J., Simmons W., Ferris C. A V1-like receptor mediates vasopressin-induced flank marking behavior in hamster hypothalamus. J Neurosci 1986, 6:2085-2089.
Ferris C.F., Melloni R.H., Koppel G., Perry K.W., Fuller R.W., Delville Y. Vasopressin/serotonin interactions in the anterior hypothalamus control aggressive behavior in golden hamsters. J Neurosci 1997, 17:4331-4340.
Albers H.E. The regulation of social recognition, social communication and aggression: vasopressin in the social behavior neural network. Horm Behav 2012, 61:283-292.
Young L.J., Flanagan-Cato L.M. Editorial comment: oxytocin, vasopressin and social behavior. Horm Behav 2012, 61:227-229.
Bielsky I.F., Hu S.B., Ren X., Terwilliger E.F., Young L.J. The V1a vasopressin receptor is necessary and sufficient for normal social recognition: a gene replacement study. Neuron 2005, 47:503-513.
Bielsky I.F., Hu S.B., Szegda K.L., Westphal H., Young L.J. Profound impairment in social recognition and reduction in anxiety-like behavior in vasopressin V1a receptor knockout mice. Neuropsychopharmacology 2004, 29:483-493.
Veenema A.H., Bredewold R., De Vries G.J. Vasopressin regulates social recognition in juvenile and adult rats of both sexes, but in sex- and age-specific ways. Horm Behav 2012, 61:50-56.
Winslow J., Hastings N., Carter C.S., Harbaugh C., Insel T. A role for central vasopressin in pair bonding in monogamous prairie voles. Nature 1993, 365:545-548.
Donaldson Z.R., Spiegel L., Young L.J. Central vasopressin V1a receptor activation is independently necessary for both partner preference formation and expression in socially monogamous male prairie voles. Behav Neurosci 2010, 124:159-163.
Insel T.R., Wang Z., Ferris C.F. Patterns of brain vasopressin receptor distribution associated with social organization in microtine rodents. J Neurosci 1994, 14:5381-5392.
Wang Z., Young L.J., Liu Y., Insel T.R. Species differences in vasopressin receptor binding are evident early in development: comparative anatomic studies in prairie and montane voles. J Comp Neurol 1997, 378:535-546.
Lim M.M., Young L.J. Vasopressin-dependent neural circuits underlying pair bond formation in the monogamous prairie vole. Neuroscience 2004, 125:35-45.
Pitkow L.J., Sharer C.A., Ren X., Insel T.R., Terwilliger E.F., Young L.J. Facilitation of affiliation and pair-bond formation by vasopressin receptor gene transfer into the ventral forebrain of a monogamous vole. J Neurosci 2001, 21:7392-7396.
Lim M.M., Wang Z., Olazábal D.E., Ren X., Terwilliger E.F., Young L.J. Enhanced partner preference in promiscuous species by manipulating the expression of a single gene. Nature 2004, 429:754-757.
Turner L.M., Young A.R., Rompler H., Schoneberg T., Phelps S.M., Hoekstra H.E. Monogamy evolves through multiple mechanisms: evidence from V1aR in deer mice. Mol Biol Evol 2010, 27:1269-1278.
Burkett J.P., Young L.J. The behavioral, anatomical and pharmacological parallels between social attachment, love and addiction. Psychopharmacology 2012, 224:1-26.
Liu Y., Curtis J.T., Wang Z.X. Vasopressin in the lateral septum regulates pair bond formation in male prairie voles (Microtus ochrogaster). Behav Neurosci 2001, 115:910-919.
Gobrogge K.L., Liu Y., Jia X., Wang Z. Anterior hypothalamic neural activation and neurochemical associations with aggression in pair-bonded male prairie voles. J Comp Neurol 2007, 502:1109-1122.
Gobrogge K.L., Liu Y., Young L.J., Wang Z. Anterior hypothalamic vasopressin regulates pair-bonding and drug-induced aggression in a monogamous rodent. Proc Natl Acad Sci USA 2009, 106:19144-19149.
Young L.J., Winslow J.T., Nilsen R., Insel T.R. Species differences in V1a receptor gene expression in monogamous and nonmonogamous voles: behavioral consequences. Behav Neurosci 1997, 111:599-605.
Young L.J., Nilsen R., Waymire K.G., MacGregor G.R., Insel T.R. Increased affiliative response to vasopressin in mice expressing the V1a receptor from a monogamous vole. Nature 1999, 400:766-768.
Hammock E.A., Young L.J. Microsatellite instability generates diversity in brain and sociobehavioral traits. Science 2005, 308:1630-1634.
Fink S., Excoffier L., Heckel G. Mammalian monogamy is not controlled by a single gene. Proc Natl Acad Sci USA 2006, 103:10956-10960.
Young L.J., Hammock E.A. On switches and knobs, microsatellites and monogamy. Trends Genet 2007, 23:209-212.
Hammock E.A., Lim M.M., Nair H.P., Young L.J. Association of vasopressin 1a receptor levels with a regulatory microsatellite and behavior. Genes Brain Behav 2005, 4:289-301.
Phelps S.M., Young L.J. Extraordinary diversity in vasopressin (V1a) receptor distributions among wild prairie voles (Microtus ochrogaster): patterns of variation and covariation. J Comp Neurol 2003, 466:564-576.
Ophir A.G., Campbell P., Hanna K., Phelps S.M. Field tests of cis-regulatory variation at the prairie vole avpr1a locus: association with V1aR abundance but not sexual or social fidelity. Horm Behav 2008, 54:694-702.
Mabry K.E., Streatfeild C.A., Keane B., Solomon N.G. avpr1a length polymorphism is not associated with either social or genetic monogamy in free-living prairie voles. Anim Behav 2011, 81:11-18.
Solomon N.G., Richmond A.R., Harding P.A., et al. Polymorphism at the avpr1a locus in male prairie voles correlated with genetic but not social monogamy in field populations. Mol Ecol 2009, 18:4680-4695.
Ophir A.G., Wolff J.O., Phelps S.M. Variation in neural V1aR predicts sexual fidelity and space use among male prairie voles in semi-natural settings. Proc Natl Acad Sci USA 2008, 105:1249-1254.
Barrett C.E., Keebaugh A.C., Ahern T.H., Bass C.E., Terwilliger E.F., Young L.J. Variation in vasopressin receptor (Avpr1a) expression creates diversity in behaviors related to monogamy in prairie voles. Horm Behav 2013, 63:518-526.
Donaldson Z.R., Young L.J. The relative contribution of proximal 59 flanking sequence and microsatellite variation on brain vasopressin 1a receptor (Avpr1a) gene expression and behavior. PLoS Genet 2013, 9:e1003729.
Young K.A., Gobrogge K.L., Liu Y., Wang Z. The neurobiology of pair bonding: insights from a socially monogamous rodent. Front Neuroendocrinol 2011, 32:53-69.
Wang Z.X., Yu G.Z., Cascio C., Liu Y., Gingrich B., Insel T.R. Dopamine D2 receptor-mediated regulation of partner preferences in female prairie voles: a mechanism for pair bonding. Behav Neurosci 1999, 113:602-611.
Gingrich B., Liu Y., Cascio C., Wang Z., Insel T.R. Dopamine D2 receptors in the nucleus accumbens are important for social attachment in female prairie voles (Microtus ochrogaster). Behav Neurosci 2000, 114:173-183.
Liu Y., Wang Z.X. Nucleus accumbens dopamine and oxytocin interact to regulate pair bond formation in female prairie voles. Neuroscience 2003, 121:537-544.
Aragona B.J., Liu Y., Curtis J.T., Stephan F.K., Wang Z. A critical role for nucleus accumbens dopamine in partner-preference formation in male prairie voles. J Neurosci 2003, 23:3483-3490.
Curtis J.T., Wang Z. Ventral tegmental area involvement in pair bonding in male prairie voles. Physiol Behav 2005, 86:338-346.
Curtis J.T., Liu Y., Aragona B.J., Wang Z. Dopamine and monogamy. Brain Res 2006, 1126:76-90.
Aragona B.J., Liu Y., Yu Y.J., et al. Nucleus accumbens dopamine differentially mediates the formation and maintenance of monogamous pair bonds. Nat Neurosci 2006, 9:133-139.
Aragona B.J., Wang Z. Opposing regulation of pair bond formation by cAMP signaling within the nucleus accumbens shell. J Neurosci 2007, 27:13352-13356.
Nelson E.E., Panksepp J. Brain substrates of infant-mother attachment: contributions of opioids, oxytocin, and norepinephrine. Neurosci Biobehav Rev 1998, 22:437-452.
Panksepp J., Herman B.H., Vilberg T., Bishop P., DeEskinazi F.G. Endogenous opioids and social behavior. Neurosci Biobehav Rev 1980, 4:473-487.
Pecina S., Berridge K.C. Opioid site in nucleus accumbens shell mediates eating and hedonic 'liking' for food: map based on microinjection Fos plumes. Brain Res 2000, 863:71-86.
Burkett J.P., Spiegel L.L., Inoue K., Murphy A.Z., Young L.J. Activation of mu-opioid receptors in the dorsal striatum is necessary for adult social attachment in monogamous prairie voles. Neuropsychopharmacology 2011, 36:2200-2210.
Pfaus J.G., Kippin T.E., Centeno S. Conditioning and sexual behavior: a review. Horm Behav 2001, 40:291-321.
Pfaus J.G., Kippin T.E., Coria-Avila G.A., et al. Who, what, where, when (and maybe even why)? How the experience of sexual reward connects sexual desire, preference, and performance. Arch Sex Behav 2012, 41:31-62.
Lim M.M., Bielsky I.F., Young L.J. Neuropeptides and the social brain: potential rodent models of autism. Int J Dev Neurosci 2005, 23:235-243.
Lim M.M., Young L.J. Neuropeptidergic regulation of affiliative behavior and social bonding in animals. Horm Behav 2006, 50:506-517.
Young L.J., Murphy Young A.Z., Hammock E.A. Anatomy and neurochemistry of the pair bond. J Comp Neurol 2005, 493:51-57.
DeVries A.C., DeVries M.B., Taymans S.E., Carter C.S. Stress has sexually dimorphic effects on pair bonding in prairie voles. Proc Natl Acad Sci USA 1996, 93:11980-11984.
DeVries A.C., DeVries M.B., Taymans S., Carter C.S. Modulation of pair bonding in female prairie voles (Microtus ochrogaster) by corticosterone. Proc Natl Acad Sci USA 1995, 92:7744-7748.
Neumann I.D., Kromer S.A., Toschi N., Ebner K. Brain oxytocin inhibits the (re)activity of the hypothalamo-pituitary-adrenal axis in male rats: involvement of hypothalamic and limbic brain regions. Regul Pept 2000, 96:31-38.
Curtis J.T., Wang Z. Glucocorticoid receptor involvement in pair bonding in female prairie voles: the effects of acute blockade and interactions with central dopamine reward systems. Neuroscience 2005, 134:369-376.
Lim M.M., Nair H.P., Young L.J. Species and sex differences in brain distribution of corticotropin-releasing factor receptor subtypes 1 and 2 in monogamous and promiscuous vole species. J Comp Neurol 2005, 487:75-92.
DeVries A.C., Guptaa T., Cardillo S., Cho M., Carter C.S. Corticotropin-releasing factor induces social preferences in male prairie voles. Psychoneuroendocrinology 2002, 27:705-714.
Lim M.M., Liu Y., Ryabinin A.E., Bai Y., Wang Z., Young L.J. CRF receptors in the nucleus accumbens modulate partner preference in prairie voles. Horm Behav 2007, 51:508-515.
Lim M.M., Tsivkovskaia N.O., Bai Y., Young L.J., Ryabinin A.E. Distribution of corticotropin-releasing factor and urocortin 1 in the vole brain. Brain Behav Evol 2006, 68:229-240.
Resendez S.L., Aragona B.J. Aversive motivation and the maintenance of monogamous pair bonding. Rev Neurosci 2013, 24:51-60.
Bosch O.J., Nair H.P., Ahern T.H., Neumann I.D., Young L.J. The CRF system mediates increased passive stress-coping behavior following the loss of a bonded partner in a monogamous rodent. Neuropsychopharmacology 2009, 34:1406-1415.
Resendez S.L., Kuhnmuench M., Krzywosinski T., Aragona B.J. kappa-Opioid receptors within the nucleus accumbens shell mediate pair bond maintenance. J Neurosci 2012, 32:6771-6784.
Dabrowska J., Hazra R., Ahern T.H., et al. Neuroanatomical evidence for reciprocal regulation of the corticotrophin-releasing factor and oxytocin systems in the hypothalamus and the bed nucleus of the stria terminalis of the rat: implications for balancing stress and affect. Psychoneuroendocrinology 2011, 36:1312-1326.
Liu Y., Young K.A., Curtis J.T., Aragona B.J., Wang Z. Social bonding decreases the rewarding properties of amphetamine through a dopamine D1 receptor-mediated mechanism. J Neurosci 2011, 31:7960-7966.
Modi M.E., Young L.J. The oxytocin system in drug discovery for autism: animal models and novel therapeutic strategies. Horm Behav 2012, 61:340-350.
Modi M.E., Young L.J. D-Cycloserine facilitates socially reinforced learning in an animal model relevant to autism spectrum disorders. Biol Psychiatry 2011, 70:298-304.
Andari E., Duhamel J.R., Zalla T., Herbrecht E., Leboyer M., Sirigu A. Promoting social behavior with oxytocin in high-functioning autism spectrum disorders. Proc Natl Acad Sci USA 2010, 107:4389-4394.
Guastella A.J., Einfeld S.L., Gray K.M., et al. Intranasal oxytocin improves emotion recognition for youth with autism spectrum disorders. Biol Psychiatry 2010, 67:692-694.
Sabatier N. alpha-Melanocyte-stimulating hormone and oxytocin: a peptide signalling cascade in the hypothalamus. J Neuroendocrinol 2006, 18:703-710.
Bales K.L., Perkeybile A.M., Conley O.G., et al. Chronic intranasal oxytocin causes long-term impairments in partner preference formation in male prairie voles. Biol Psychiatry 2013, 74:180-188.
Young L.J. When too much of a good thing is bad: chronic oxytocin, development, and social impairments. Biol Psychiatry 2013, 74:160-161.
McGraw L.A., Young L.J. The prairie vole: an emerging model organism for understanding the social brain. Trends Neurosci 2010, 33:103-109.
Hammock E.A., Young L.J. Oxytocin, vasopressin and pair bonding: implications for autism. Philos Trans R Soc Lond B Biol Sci 2006, 361:2187-2198.
Bales K.L., Perkeybile A.M. Developmental experiences and the oxytocin receptor system. Horm Behav 2012, 61:313-319.
Bales K.L., Lewis-Reese A.D., Pfeifer L.A., Kramer K.M., Carter C.S. Early experience affects the traits of monogamy in a sexually dimorphic manner. Dev Psychobiol 2007, 49:335-342.
Ahern T.H., Young L.J. The impact of early life family structure on adult social attachment, alloparental behavior, and the neuropeptide systems regulating affiliative behaviors in the monogamous prairie vole (Microtus ochrogaster). Front Behav Neurosci 2009, 3:17.
Ahern T.H., Hammock E.A., Young L.J. Parental division of labor, coordination, and the effects of family structure on parenting in monogamous prairie voles (Microtus ochrogaster). Dev Psychobiol 2011, 53:118-131.
Kojima S., Stewart R.A., Demas G.E., Alberts J.R. Maternal contact differentially modulates central and peripheral oxytocin in rat pups during a brief regime of mother-pup interaction that induces a filial huddling preference. J Neuroendocrinol 2012, 24:831-840.
Bales K.L., Carter C.S. Developmental exposure to oxytocin facilitates partner preferences in male prairie voles (Microtus ochrogaster). Behav Neurosci 2003, 117:854-859.
Bales K.L., van Westerhuyzen J.A., Lewis-Reese A.D., Grotte N.D., Lanter J.A., Carter C.S. Oxytocin has dose-dependent developmental effects on pair-bonding and alloparental care in female prairie voles. Horm Behav 2007, 52:274-279.
Bales K.L., Plotsky P.M., Young L.J., et al. Neonatal oxytocin manipulations have long-lasting, sexually dimorphic effects on vasopressin receptors. Neuroscience 2007, 144:38-45.
Goodson J.L., Lindberg L., Johnson P. Effects of central vasotocin and mesotocin manipulations on social behavior in male and female zebra finches. Horm Behav 2004, 45:136-143.
Kabelik D., Klatt J.D., Kingsbury M.A., Goodson J.L. Endogenous vasotocin exerts context-dependent behavioral effects in a semi-naturalistic colony environment. Horm Behav 2009, 56:101-107.
Pedersen A., Tomaszycki M.L. Oxytocin antagonist treatments alter the formation of pair relationships in zebra finches of both sexes. Horm Behav 2012, 62:113-119.
Klatt J.D., Goodson J.L. Oxytocin-like receptors mediate pair bonding in a socially monogamous songbird. Proc Biol Sci 2013, 280:20122396.
Smiley K.O., Vahaba D.M., Tomaszycki M.L. Behavioral effects of progesterone on pair bonding and partner preference in the female zebra finch (Taeniopygia guttata). Behav Processes 2012, 90:210-216.
Tomaszycki M.L., Banerjee S.B., Adkins-Regan E. The role of sex steroids in courtship, pairing and pairing behaviors in the socially monogamous zebra finch. Horm Behav 2006, 50:141-147.
Smith A.S., Agmo A., Birnie A.K., French J.A. Manipulation of the oxytocin system alters social behavior and attraction in pair-bonding primates, Callithrix penicillata. Horm Behav 2010, 57:255-262.
Schorscher-Petcu A., Dupre A., Tribollet E. Distribution of vasopressin and oxytocin binding sites in the brain and upper spinal cord of the common marmoset. Neurosci Lett 2009, 461:217-222.
Jarcho M.R., Mendoza S.P., Mason W.A., Yang X., Bales K.L. Intranasal vasopressin affects pair bonding and peripheral gene expression in male Callicebus cupreus. Genes Brain Behav 2011, 10:375-383.
Bales K.L., Mason W.A., Catana C., Cherry S.R., Mendoza S.P. Neural correlates of pair-bonding in a monogamous primate. Brain Res 2007, 1184:245-253.
Schneiderman I., Zagoory-Sharon O., Leckman J.F., Feldman R. Oxytocin during the initial stages of romantic attachment: relations to couples' interactive reciprocity. Psychoneuroendocrinology 2012, 37:1277-1285.
Szeto A., McCabe P.M., Nation D.A., et al. Evaluation of enzyme immunoassay and radioimmunoassay methods for the measurement of plasma oxytocin. Psychosom Med 2011, 73:393-400.
Scheele D., Striepens N., Gunturkun O., et al. Oxytocin modulates social distance between males and females. J Neurosci 2012, 32:16074-16079.
Walum H., Westberg L., Henningsson S., et al. Genetic variation in the vasopressin receptor 1a gene (AVPR1A) associates with pair-bonding behavior in humans. Proc Natl Acad Sci USA 2008, 105:14153-14156.
Walum H., Lichtenstein P., Neiderhiser J.M., et al. Variation in the oxytocin receptor gene is associated with pair-bonding and social behavior. Biol Psychiatry 2012, 71:419-426.
Zeki S. The neurobiology of love. FEBS Lett 2007, 581:2575-2579.
Bartels A., Zeki S. The neural basis of romantic love. Neuroreport 2000, 11:3829-3834.
Bartels A., Zeki S. The neural correlates of maternal and romantic love. Neuroimage 2004, 21:1155-1166.
Zeki S., Romaya J.P. The brain reaction to viewing faces of opposite- and same-sex romantic partners. PloS One 2010, 5:e15802.
Aron A., Fisher H., Mashek D.J., Strong G., Li H., Brown L.L. Reward, motivation, and emotion systems associated with early-stage intense romantic love. J Neurophysiol 2005, 94:327-337.
Fisher H.E., Brown L.L., Aron A., Strong G., Mashek D. Reward, addiction, and emotion regulation systems associated with rejection in love. J Neurophysiol 2010, 104:51-60.
Lutchmaya S., Baron-Cohen S., Raggatt P. Foetal testosterone and eye contact in 12-month-old human infants. Infant Behav Dev 2002, 25:327-335.
Auyeung B., Baron-Cohen S., Ashwin E., et al. Fetal testosterone predicts sexually differen-tiated childhood behavior in girls and in boys. Psychol Sci 2009, 20:144-148.
Auyeung B., Knickmeyer R., Ashwin E., Taylor K., Hackett G., Baron-Cohen S. Effects of fetal testosterone on visuospatial ability. Arch Sex Behav 2012, 41:571-581.
Lombardo M.V., Ashwin E., Auyeung B., et al. Fetal testosterone influences sexually dimorphic gray matter in the human brain. J Neurosci 2012, 32:674-680.
McGraw L.A., Davis J.K., Thomas P.J., Young L.J., Thomas J.W. BAC-based sequencing of behaviorally-relevant genes in the prairie vole. PloS One 2012, 7:e29345.
McGraw L.A., Davis J.K., Lowman J.J., et al. Development of genomic resources for the prairie vole (Microtus ochrogaster): construction of a BAC library and vole-mouse comparative cytogenetic map. BMC Genomics 2010, 11:70.
McGraw L.A., Davis J.K., Young L.J., Thomas J.W. A genetic linkage map and comparative mapping of the prairie vole (Microtus ochrogaster) genome. BMC Genet 2011, 12:60.
Donaldson Z.R., Yang S.H., Chan A.W., Young L.J. Production of germline transgenic prairie voles (Microtus ochrogaster) using lentiviral vectors. Biol Reprod 2009, 81:1189-1195.
Manoli D.S., Subramanyam D., Carey C., et al. Generation of induced pluripotent stem cells from the prairie vole. PloS One 2012, 7:e38119.
