Article (Scientific journals)
Cervical cancer in the Netherlands 1989-1998: Decrease of squamous cell carcinoma in older women, increase of adenocarcinoma in younger women.
BULK, Saskia; Visser, Otto; Rozendaal, Lawrence et al.
2005In International Journal of Cancer, 113 (6), p. 1005-9
Peer Reviewed verified by ORBi
 

Files


Full Text
Bulk 14.pdf
Publisher postprint (79.5 kB)
Request a copy

All documents in ORBi are protected by a user license.

Send to



Details



Keywords :
Adenocarcinoma/epidemiology/pathology; Adolescent; Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell/epidemiology/pathology; Female; Humans; Incidence; Middle Aged; Neoplasm Staging; Netherlands/epidemiology; Uterine Cervical Neoplasms/epidemiology/pathology
Abstract :
[en] Cervical cancer is a preventable disease, occurring in relatively young women. In the Netherlands, population-based cervical screening aims at women aged 30-60 years. We performed a population-based study of the incidence of invasive cervical cancer in the Netherlands to evaluate trends, with emphasis on age at time of diagnosis. Histologic diagnosis was retrieved from the Netherlands Cancer Registry for all women residing in the Netherlands with invasive cervical cancer between January 1, 1989, and December 31, 1998. In this 10-year period, the incidence rate of squamous cell carcinoma decreased significantly from 7.1/100,000 to 6.1/100,000 (p < 0.001), with the greatest decrease in women aged 60-74 (-5.5%). While the overall incidence rate of adenocarcinoma remained stable, it increased in women aged 15-29 (+15.8%) and in women aged 30-44 (+2.5%), though the number of cases was small. For squamous cell carcinoma, the incidence of stage II at diagnosis decreased most (-2.7%). There was no change in stage at diagnosis for adenocarcinoma. Most cases of cervical cancer, 60.5%, were detected between ages 30 and 60 years, i.e., the Dutch screening age interval. Cervical cancer in women below age 30 contributed 5.0% to the total incidence, with 3.0% occurring between ages 27 and 29. Thus, screening for cervical cancer in the Netherlands is associated with a decrease in the incidence of squamous cell carcinoma and adenocarcinoma incidence appears to be increasing in younger women.
Disciplines :
Genetics & genetic processes
Author, co-author :
BULK, Saskia ;  Centre Hospitalier Universitaire de Liège - CHU > Génétique
Visser, Otto
Rozendaal, Lawrence
Verheijen, Rene H. M.
Meijer, Chris J. L. M.
Language :
English
Title :
Cervical cancer in the Netherlands 1989-1998: Decrease of squamous cell carcinoma in older women, increase of adenocarcinoma in younger women.
Publication date :
2005
Journal title :
International Journal of Cancer
ISSN :
0020-7136
eISSN :
1097-0215
Publisher :
John Wiley & Sons, Hoboken, United States - New York
Volume :
113
Issue :
6
Pages :
1005-9
Peer reviewed :
Peer Reviewed verified by ORBi
Commentary :
(c) 2004 Wiley-Liss, Inc.
Available on ORBi :
since 23 May 2015

Statistics


Number of views
33 (0 by ULiège)
Number of downloads
0 (0 by ULiège)

Scopus citations®
 
125
Scopus citations®
without self-citations
111
OpenCitations
 
109

Bibliography


Similar publications



Contact ORBi