ORBi: Arnould Valérie - Genetic analysis of lactoferrin content in bovine milk

Reference : Genetic analysis of lactoferrin content in bovine milk


	Document type :	Scientific journals : Article
	Discipline(s) :	Life sciences : Genetics & genetic processes Life sciences : Food science Life sciences : Animal production & animal husbandry
	To cite this reference:	http://hdl.handle.net/2268/18145

Title :	Genetic analysis of lactoferrin content in bovine milk
Language :	English
Author, co-author :	Arnould, Valérie [Université de Liège - ULg > Sciences agronomiques > Zootechnie >]
	Soyeurt, Hélène [Université de Liège - ULg > Sciences agronomiques > Zootechnie >]
	Gengler, Nicolas [Université de Liège - ULg > Sciences agronomiques > Zootechnie >]
	Colinet, Frédéric [Faculté Universitaire des Sciences Agronomiques de Gembloux - FUSAGx > > Biologie animale et microbienne > >]
	Georges, Marielle [Faculté Universitaire des Sciences Agronomiques de Gembloux - FUSAGx > > Biologie animale et microbienne > >]
	Bertozzi, Carlo [Association Wallonne de l'Elevage - AWE > > > >]
	Portetelle, Daniel [Université de Liège - ULg > Chimie et bio-industries > Biologie animale et microbienne >]
	Renaville, Robert [Université de Liège - ULg > Chimie et bio-industries > Biologie animale et microbienne >]
Publication date :	2009
Journal title :	Journal of Dairy Science
Publisher :	American Dairy Science Association
Volume :	92
Issue/season :	5
Pages :	2151-2158
Audience :	International
ISSN :	0022-0302
e-ISSN :	1525-3198
City :	Champaign
Country :	IL
Keywords :	[en] Animals ; Cattle/genetics ; Fats/analysis ; Female ; Gene Frequency ; Lactation/genetics ; Lactoferrin/chemistry/genetics ; Milk/chemistry/cytology ; Milk Proteins/analysis ; Polymorphism, Single Nucleotide/genetics ; Spectrophotometry, Infrared
Abstract :	[en] Bovine lactoferrin (LF) is mainly present in milk and shows important physiological and biological functions. The aim of this study was to estimate the heritability and correlation values of LF content in bovine milk with different economic traits as milk yield (MY), fat and protein percentages, and somatic cell score (SCS). Variance components of the studied traits were estimated by REML using a multiple-trait mixed model. The obtained heritability (0.22) for LF content predicted using mid-infrared spectrometry (pLF) suggested the possibility of animal selection based on the increase of LF content in milk. The phenotypic and genetic correlation values calculated between pLF and SCS were moderate (0.31 and 0.24, respectively). Furthermore, a preliminary study of bovine LF gene polymorphism effects was performed on the same production traits. By PCR, all exons of the LF gene were amplified and then sequenced. Three new polymorphisms were detected in exon 2, exon 11, and intron 8. We examined the effects of LF gene polymorphisms of exons 2, 4, 9, 11, and 15, and intron 8 on pLF, MY, fat and protein percentages, and SCS. The different observed effects did not reach a significant level probably because of the characteristics of the studied population. However, the results were promising, and LF may be a potential indicator of mastitis. Further studies are necessary to evaluate the effect of genetic selection based on LF content on the improvement of mastitis resistance.
Target :	Researchers
Permalink :	http://hdl.handle.net/2268/18145
DOI :	10.3168/jds.2008-1255
Other URL :	http://jds.fass.org/cgi/reprint/92/5/2151
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