Article (Scientific journals)
Chronic Cutaneous Hyalophomycosis by Paecilomyces
BOUFFLETTE, Nicolas; Arrese Estrada, Jorge; LEONARD, Philippe et al.
2014In Open Dermatology Journal, 8, p. 4-7
 

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Keywords :
Hyalohyphomycosis; immunosuppression; paecilomyceslilacinus; voriconazole; skin infection
Abstract :
[en] Paecilomyces lilacinus is a ubiquitous saprophytic fungus that rarely causes infections in humans, frequently affecting the eyes and the skin. Cutaneous and subcutaneous infections mainly occur in immunocompromised hosts but have occasionally been reported in immunocompetent patients. The clinical spectrum is highly heterogeneous and diagnosis is often delayed. A 60-year-old woman with idiopathic chronic necrotizing vasculitis treated since 10 years with a series of immunosuppressive therapies presented since three years various clinical presentations of chronic hyalohyphomycosis caused by P. lilacinus. Diagnosis was only obtained three years after the first clinical signs, following the histologic analysis of the surgical excision of a cutaneous abscess. Treatment with oral voriconazole was successful. This case report illustrates the highly heterogeneous clinical aspects of hyalohyphomycosis by P. lilacinus leading to a delay in diagnosis and treatment, particularly in the immunosuppressed patient.
Disciplines :
Dermatology
Author, co-author :
BOUFFLETTE, Nicolas ;  Centre Hospitalier Universitaire de Liège - CHU > Dermatologie
Arrese Estrada, Jorge ;  Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Anatomie et cytologie pathologiques
LEONARD, Philippe ;  Centre Hospitalier Universitaire de Liège - CHU > Maladies infectieuses et médecine interne générale
NIKKELS, Arjen ;  Centre Hospitalier Universitaire de Liège - CHU > Dermatologie
Language :
English
Title :
Chronic Cutaneous Hyalophomycosis by Paecilomyces
Publication date :
2014
Journal title :
Open Dermatology Journal
eISSN :
1874-3722
Publisher :
Bentham Science Publishers, United Arab Emirates
Volume :
8
Pages :
4-7
Available on ORBi :
since 06 February 2015

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