Y a-t-il une place pour les SPRMs avant PMA?

Myomas may account for infertility by modifying the uterine cavity’s anatomy and intra-uterine
signalling pathways leading to a hostile environment for embryo implantation. In vitro fertilization (IVF) alone is not always sufficient to result in pregnancy. While surgery, if performed before IVF, can increase the pregnancy rate, selective progesterone receptor modulator such as ulipristal acetate can decrease smooth muscle cell proliferation and induce apoptosis. In addition, ulipristal acetate when used before surgery could reduce surgical complications and induce a decrease in the myoma size before performing IVF.