La thermoplastie bronchique dans le traitement de l'asthme sévère de l'adulte.

Asthma exacerbation; Asthma phenotypes; Asthme sévère; Bronchial endoscopy; Bronchial thermoplasty; Endoscopie bronchique; Exacerbation; Phénotypes de l’asthme; Severe asthma; Thermoplastie bronchique

Abstract :

[en] Bronchial thermoplasty is a recent endoscopic technique for the treatment of severe asthma. It is an innovative treatment whose clinical efficacy and safety are beginning to be better understood. Since this is a device-based treatment, the evaluation procedure of risks and benefits is different that for pharmaceutical products; safety aspects, regulatory requirements, study design and the assessment of the magnitude of effects may all be different. The mechanism of action and optimal patient selection need to be assessed further in rigorous clinical and scientific studies. This technique is in harmony with the development of personalised medicine in the 21st century. It should be developed further in response to the numerous challenges and needs not yet met in the management of severe asthma.

Disciplines :

Cardiovascular & respiratory systems

Author, co-author :

Chanez, P.

Boulet, L.-P.

Brillet, P.-Y.

Joos, G.

Laviolette, M.

Louis, Renaud ; Université de Liège - ULiège > Département des sciences cliniques > Pneumologie - Allergologie

Rochat, T.

Soccal, P.

Aubier, M.

Language :

French

Title :

La thermoplastie bronchique dans le traitement de l'asthme sévère de l'adulte.

Alternative titles :

[en] Bronchial thermoplasty in the treatment of severe adult asthma.

Publication date :

February 2015

Journal title :

Revue des Maladies Respiratoires

ISSN :

0761-8425

eISSN :

1776-2588

Publisher :

Elsevier

Volume :

Pages :

37-109

Peer reviewed :

Peer Reviewed verified by ORBi

Additional URL :

http://www.sciencedirect.com/science/article/pii/S0761842514012595

Commentary :

Available on ORBi :

since 16 January 2015

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