Article (Scientific journals)
In vitro characterization of the Bacillus subtilis protein tyrosine phosphatase YwqE
Mijakovic, Ivan; Musumeci, Lucia; Tautz, Lutz et al.
2005In Journal of Bacteriology, 187 (10), p. 3384-90
Peer Reviewed verified by ORBi
 

Files


Full Text
BsubYwlE2005.pdf
Publisher postprint (434.27 kB)
Download

All documents in ORBi are protected by a user license.

Send to



Details



Keywords :
LMPTP; YwqE; phasphatases
Abstract :
[en] Both gram-negative and gram-positive bacteria possess protein tyrosine phosphatases (PTPs) with a catalytic Cys residue. In addition, many gram-positive bacteria have acquired a new family of PTPs, whose first characterized member was CpsB from Streptococcus pneumoniae. Bacillus subtilis contains one such CpsB-like PTP, YwqE, in addition to two class II Cys-based PTPs, YwlE and YfkJ. The substrates for both YwlE and YfkJ are presently unknown, while YwqE was shown to dephosphorylate two phosphotyrosine-containing proteins implicated in UDP-glucuronate biosynthesis, YwqD and YwqF. In this study, we characterize YwqE, compare the activities of the three B. subtilis PTPs (YwqE, YwlE, and YfkJ), and demonstrate that the two B. subtilis class II PTPs do not dephosphorylate the physiological substrates of YwqE.
Research center :
Microbial Physiology and Genetics Group, BioCentrum
Technical University of Denmark
Inflammatory and Infectious Disease Center, The Burnham Institute
Microbiologie et Génétique Moléculaire, CNRS/INRA/INA-PG
Disciplines :
Microbiology
Author, co-author :
Mijakovic, Ivan
Musumeci, Lucia ;  Université de Liège - ULiège > GIGA-Research
Tautz, Lutz
Petranovic, Dina
Edwards, Robert
Jensen, Peter Ruhdal
Mustelin, Tomas
Deutscher, Josef
Bottini, Nunzio
Language :
English
Title :
In vitro characterization of the Bacillus subtilis protein tyrosine phosphatase YwqE
Publication date :
May 2005
Journal title :
Journal of Bacteriology
ISSN :
0021-9193
eISSN :
1098-5530
Publisher :
American Society for Microbiology (ASM), Washington, United States - District of Columbia
Volume :
187
Issue :
10
Pages :
3384-90
Peer reviewed :
Peer Reviewed verified by ORBi
Funders :
NIH - National Institutes of Health [US-MD] [US-MD]
INRA - Institut National de la Recherche Agronomique [FR]
Danish National Research Council
CNRS - Centre National de la Recherche Scientifique [FR]
Available on ORBi :
since 06 January 2015

Statistics


Number of views
51 (1 by ULiège)
Number of downloads
187 (1 by ULiège)

Scopus citations®
 
40
Scopus citations®
without self-citations
25
OpenCitations
 
33

Bibliography


Similar publications



Contact ORBi