[en] The aim of this open trial was to assess the antidepressant/anxiolytic effects of oxytocin used as an adjunct to antidepressant in treatment-resistant depression. Fourteen patients, who have not responded to 40mg of escitalopram, received intranasal synthetic oxytocin during 4 weeks, in association with antidepressant. This is the first open trial study suggesting OT in association with escitalopram significantly reduced scores on Hamilton Depression Rating Scale.
Disciplines :
Psychiatry
Author, co-author :
Scantamburlo, Gabrielle ; Université de Liège - ULiège > Département des sciences cliniques > Psychiatrie et psychologie médicale
Hansenne, Michel ; Université de Liège - ULiège > Département de Psychologie : cognition et comportement > Psycho. de la personnalité et des différences individuelles
Geenen, Vincent ; Université de Liège - ULiège > Centre d'immunologie
Legros, Jean-Jacques ; Université de Liège - ULiège > Département des sciences cliniques > Département des sciences cliniques
Ansseau, Marc ; Université de Liège - ULiège > Département des sciences cliniques > Psychiatrie et psychologie médicale
Language :
English
Title :
Additional intranasal oxytocin to escitalopram improves depressive symptoms in resistant depression: An open trial.
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