Article (Scientific journals)
Combined enzymatic synthesis of nucleotide (deoxy) sugars from sucrose and nucleoside monophosphates
Zervosen, Astrid; Stein, Andreas; Adrian, Holger et al.
1996In Tetrahedron, 52 (7), p. 2395-2404
Peer Reviewed verified by ORBi
 

Files


Full Text
tetrahedron1996.pdf
Publisher postprint (511.53 kB)
Request a copy

All documents in ORBi are protected by a user license.

Send to



Details



Keywords :
nucleotide sugar; enzymatic synthesis
Abstract :
[en] Abstract: The synthesis of NDP-glucose 3a-d (N= A, C, U, dU) with sucrose synthase B was combined with the enzymatic synthesis of nucleoside diphosphates 2a-d from their corresponding nucleoside monophosphates la-d by different kinases A. Further combination with recombinant dTDP-glucose 4,6-dehydratase D enabled us to synthesize dUDP-6-deoxy-alpha-D-xylo-4-hexulose 5 from ld on a preparative scale. By using the repetitive batch technique the enzymatic syntheses of nucleotide (deoxy) sugars 3a-d, 5 could be realized on a 0.1 - 0.5 g scale.
Disciplines :
Biochemistry, biophysics & molecular biology
Author, co-author :
Zervosen, Astrid ;  Université de Liège - ULiège > Centre de recherches du cyclotron
Stein, Andreas
Adrian, Holger
Elling, Lothar
Language :
English
Title :
Combined enzymatic synthesis of nucleotide (deoxy) sugars from sucrose and nucleoside monophosphates
Publication date :
1996
Journal title :
Tetrahedron
ISSN :
0040-4020
Publisher :
Pergamon Press, Oxford, United Kingdom
Volume :
52
Issue :
7
Pages :
2395-2404
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 23 July 2009

Statistics


Number of views
72 (5 by ULiège)
Number of downloads
3 (3 by ULiège)

Scopus citations®
 
35
Scopus citations®
without self-citations
18
OpenCitations
 
32

Bibliography


Similar publications



Contact ORBi