Article (Scientific journals)
Dramatic osteonecrosis of the jaw associated with oral bisphosphonates, periodontitis and dental implant removal
Ayora, A F; HERION, Francine; ROMPEN, Eric et al.
2015In Journal of Clinical Periodontology, 42, p. 190-195
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Abstract :
[en] Osteoporosis affects millions of elderly patients, and anti-resorptive drugs (ARD) such as bisphosphonates (BP) represent the first-line therapy. Despite the benefits related to the use of these medications, osteonecrosis of the jaw is a significant complication in a subset of patients receiving these drugs. CASE PRESENTATION: This report documents a case of dramatic bisphosphonate-related osteonecrosis associated with periodontitis and dental implant removal in an osteoporotic patient treated with per os bisphosphonates for an uninterrupted period of 15 years. CONCLUSION: The aim of this report was to discuss the administration period of BP in the treatment of osteoporosis, the decision-making and clinical management of severe MRONJ and the indications for dental implant placement in these specific patients.
Research center :
d‐BRU - Dental Biomaterials Research Unit - ULiège [BE]
Disciplines :
General & internal medicine
Author, co-author :
Ayora, A F
HERION, Francine ;  Centre Hospitalier Universitaire de Liège - CHU > Médecine dentaire
ROMPEN, Eric ;  Centre Hospitalier Universitaire de Liège - CHU > Médecine dentaire
Reginster, Jean-Yves  ;  Université de Liège - ULiège > Département des sciences de la santé publique > Santé publique, Epidémiologie et Economie de la santé
Magremanne, M
LAMBERT, France ;  Centre Hospitalier Universitaire de Liège - CHU > Médecine dentaire
Language :
English
Title :
Dramatic osteonecrosis of the jaw associated with oral bisphosphonates, periodontitis and dental implant removal
Publication date :
2015
Journal title :
Journal of Clinical Periodontology
ISSN :
0303-6979
eISSN :
1600-051X
Publisher :
Wiley
Volume :
42
Pages :
190-195
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 21 October 2014

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