Article (Scientific journals)
Bone marrow stromal stem cells transplantation in mice with acute spinal cord injury
Neirinckx, Virginie; Rogister, Bernard; Franzen, Rachelle et al.
2014In Methods in Molecular Biology, 1213
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Abstract :
[en] Spinal cord injured experimental animals are widely used for studying pathophysiological processes after central nervous system acute traumatic lesion and elaborating therapeutic solutions, some of them based on stem cell transplantation. Here, we describe a protocol of spinal cord contusion in C57BL/6J mice, directly followed by bone marrow stromal stem cells transplantation. This model allows for the characterization of neuroprotective and neurorestorative abilities of these stem cells in a context of spinal cord trauma.
Disciplines :
Biochemistry, biophysics & molecular biology
Author, co-author :
Neirinckx, Virginie ;  Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Biochimie et physiologie générales, et biochimie humaine
Rogister, Bernard  ;  Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Biochimie et physiologie générales, et biochimie humaine
Franzen, Rachelle  ;  Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Neuro-anatomie
Wislet, Sabine  ;  Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Biochimie et physiologie générales, et biochimie humaine
Language :
English
Title :
Bone marrow stromal stem cells transplantation in mice with acute spinal cord injury
Publication date :
2014
Journal title :
Methods in Molecular Biology
ISSN :
1064-3745
eISSN :
1940-6029
Publisher :
Humana Press, Totowa, United States - New Jersey
Special issue title :
Animal Models for Stem Cell Therapy
Volume :
1213
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 13 October 2014

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