Article (Scientific journals)
Chronobiology, excessive daytime sleepiness and depression: Is there a link?
Chellappa, Sarah Laxhmi; Schroder, Carmen; Cajochen, Christian
2009In Sleep Medicine, 10 (5), p. 505-14
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Keywords :
Arousal/physiology; Circadian Rhythm/physiology; Depressive Disorder/complications/physiopathology; Disorders of Excessive Somnolence/diagnosis/etiology/therapy; Humans
Abstract :
[en] The complaint of excessive daytime sleepiness (EDS), commonly encountered in clinical practice, may arise from a variety of psychiatric disorders, most importantly depression. Even though EDS frequently leads depressed patients to seek medical assistance, it is commonly under-evaluated and under-diagnosed. Therefore, a comprehensive understanding and management of EDS is essential in the clinical assessment of depression. Within a theoretical framework, a chronobiological approach may shed new light on the complex interaction of EDS and depression. In this review, studies on EDS and depression are summarized and discussed within the context of circadian and sleep regulatory mechanisms. Furthermore, potential chronobiological therapeutic strategies are proposed to address some of the unmet needs in the treatment of EDS and depression.
Disciplines :
Psychiatry
Author, co-author :
Chellappa, Sarah Laxhmi ;  Université de Liège - ULiège > Centre de recherches du cyclotron
Schroder, Carmen
Cajochen, Christian
Language :
English
Title :
Chronobiology, excessive daytime sleepiness and depression: Is there a link?
Publication date :
2009
Journal title :
Sleep Medicine
ISSN :
1389-9457
eISSN :
1878-5506
Publisher :
Elsevier, Netherlands
Volume :
10
Issue :
5
Pages :
505-14
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 22 August 2014

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