|Reference : Younger age as a bad prognostic factor in patients with carcinoma of the cervix.|
|Scientific journals : Article|
|Human health sciences : Oncology|
Human health sciences : Hematology
|Younger age as a bad prognostic factor in patients with carcinoma of the cervix.|
|Delaloye, J-F [ > > ]|
|Pampallona, S [ > > ]|
|COUCKE, Philippe [Centre Hospitalier Universitaire Vaudois > > Radiothérapie > > >]|
|De Grandi, P [ > > ]|
|European Journal of Obstetrics & Gynecology & Reproductive Biology|
|[en] age ; Overrall survival ; Cervix carcinoma|
|[en] Objective: To verify the influence of age on the prognosis of cervix carcinoma. Study design: Five hundred and sixty eight patients
treated for a FIGO stage IB-IVA with radical irradiation in the Centre Hospitalier Universitaire Vaudois of Lausanne were subdivided
according to the following age categories: _<45, 46-60, 61-69 and > 70 years. Taking the 46-60 years age group as the
reference, the hazard ratios (HR) of death and corresponding 95% confidence intervals (95% CI) were estimated by means of a
Cox multivariate analysis. Results: The 5-year survival rates were, respectively, 57%, 67%, 60% and 45%. For the youngest women
the risk of death was significantly increased (HR = 2.00, 95% CI [1.32-3.00]) and was even more accentuated in advanced stages.
Conclusion: Age under 45 years is a bad prognostic factor in carcinoma of the cervix.
|Researchers ; Professionals|
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