|Reference : Quantitative short-term study of Anal sphincter function after chemoradiation for rectal...|
|Scientific journals : Article|
|Human health sciences : Hematology|
Human health sciences : Oncology
|Quantitative short-term study of Anal sphincter function after chemoradiation for rectal cancer|
|Gervaz, Pascal [ > > ]|
|Rotholtz, Nicolas [ > > ]|
|Pisano, Michele [ > > ]|
|Kaplan, Edward [ > > ]|
|Secic, Michele [ > > ]|
|COUCKE, Philippe [Cleveland Clinic Foundation > > > >]|
|Pikarsky, Alon [ > > ]|
|Efron, Jonathan [ > > ]|
|Wexner, Steven [ > > ]|
|Langenbeck's Archives of Surgery|
|Springer Science & Business Media B.V.|
|[en] Pelvic irradiation ; anal sphincter function ; radiotherapy ; chemoradiotherapy ; prostectomy ; coloanal anastomosis|
|[en] Hypothesis: Pelvic irradiation adversely affects anal
sphincter function after proctectomy with coloanal anastomosis
for low rectal and middle rectal (,10 cm from
the anal verge) tumors.
Design: Case-control study.
Setting: Private, tertiary care referral center.
Patients: Patients treated for low rectal adenocarcinoma
between January 1, 1994, and October 31, 1999.
Interventions: Anal manometric data were prospectively
collected at the time of initial diagnosis and before
Main Outcome Measures: Mean and maximum resting
pressures (RPs) and squeeze pressures, threshold volume
for sensation, and maximal tolerable volume.
Results: Twenty-three patients in the surgery group and
19 in the chemoradiotherapy group were considered for
|Researchers ; Professionals|
|File(s) associated to this reference|
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