Reference : Quantitative short-term study of Anal sphincter function after chemoradiation for rec...
Scientific journals : Article
Human health sciences : Hematology
Human health sciences : Oncology
http://hdl.handle.net/2268/16983
Quantitative short-term study of Anal sphincter function after chemoradiation for rectal cancer
English
Gervaz, Pascal [ > > ]
Rotholtz, Nicolas [ > > ]
Pisano, Michele [ > > ]
Kaplan, Edward [ > > ]
Secic, Michele [ > > ]
COUCKE, Philippe mailto [Cleveland Clinic Foundation > > > >]
Pikarsky, Alon [ > > ]
Efron, Jonathan [ > > ]
Wexner, Steven [ > > ]
2001
Langenbeck's Archives of Surgery
Springer Science & Business Media B.V.
136
192-196
Yes (verified by ORBi)
International
1435-2443
1435-2451
[en] Pelvic irradiation ; anal sphincter function ; radiotherapy ; chemoradiotherapy ; prostectomy ; coloanal anastomosis
[en] Hypothesis: Pelvic irradiation adversely affects anal
sphincter function after proctectomy with coloanal anastomosis
for low rectal and middle rectal (,10 cm from
the anal verge) tumors.
Design: Case-control study.
Setting: Private, tertiary care referral center.
Patients: Patients treated for low rectal adenocarcinoma
between January 1, 1994, and October 31, 1999.
Interventions: Anal manometric data were prospectively
collected at the time of initial diagnosis and before
ileostomy closure.
Main Outcome Measures: Mean and maximum resting
pressures (RPs) and squeeze pressures, threshold volume
for sensation, and maximal tolerable volume.
Results: Twenty-three patients in the surgery group and
19 in the chemoradiotherapy group were considered for
Researchers ; Professionals
http://hdl.handle.net/2268/16983

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