Article (Scientific journals)
Gender dependent accumulation of dioxins in smokers
Fierens, S.; Eppe, Gauthier; De Pauw, Edwin et al.
2005In Occupational and Environmental Medicine, 62 (1), p. 61-62
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Abstract :
[en] Aims: To evaluate the contribution of tobacco smoking to dioxin accumulation. Methods: Dioxin (17 PCDD/F) concentrations in fasting blood from 251 subjects ( 161 never smokers, 54 past smokers, and 36 current smokers) were quantified. Results: Whereas serum dioxin concentrations of male smokers were on average 40% higher than those of nonsmokers, in women, smoking was associated with significantly lower serum dioxin levels. A synergistic potentiation of dioxin metabolism by tobacco smoke in women is postulated to explain these paradoxical findings. Conclusions: Current smoking is associated with gender dependent effects on dioxin body burden and is a potential source of confounding in human studies using blood dioxins as indicators of exposure.
Disciplines :
Public health, health care sciences & services
Author, co-author :
Fierens, S.
Eppe, Gauthier  ;  Université de Liège - ULiège > Centre interfac. d'analyse des résidus en traces (CART)
De Pauw, Edwin  ;  Université de Liège - ULiège > Chimie physique, spectrométrie de masse
Bernard, A.
Language :
English
Title :
Gender dependent accumulation of dioxins in smokers
Publication date :
January 2005
Journal title :
Occupational and Environmental Medicine
ISSN :
1351-0711
eISSN :
1470-7926
Publisher :
B M J Publishing Group, London, United Kingdom
Volume :
62
Issue :
1
Pages :
61-62
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 13 July 2009

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