Reference : Translocation (2;3)(p21;q26) as the sole anomaly in a case of primary myelofibrosis.
Scientific journals : Article
Life sciences : Genetics & genetic processes
Human health sciences : Hematology
http://hdl.handle.net/2268/10055
Translocation (2;3)(p21;q26) as the sole anomaly in a case of primary myelofibrosis.
English
Herens, Christian mailto [Centre Hospitalier Universitaire de Liège - CHU > > Génétique >]
Hermanne, Jean-Philippe [Centre Hospitalier Universitaire de Liège - CHU >]
Tassin, Françoise mailto [Centre Hospitalier Universitaire de Liège - CHU > > Hématologie biologique et immuno hématologie >]
Fassotte, Marie-France mailto [Centre Hospitalier Universitaire de Liège - CHU > > Hématologie clinique >]
Thiry, Albert mailto [Université de Liège - ULg > > Anatomie pathologique >]
Jamar, Mauricette mailto [Université de Liège - ULg > > Génétique >]
Schaaf, Nicole mailto [Centre Hospitalier Universitaire de Liège - CHU > > Hématologie biologique et immuno hématologie >]
Fillet, Georges mailto [Centre Hospitalier Universitaire de Liège - CHU > > Hématologie clinique >]
Koulischer, Lucien [Université de Liège - ULg > > Relations académiques et scientifiques (Médecine) >]
1999
Cancer Genetics & Cytogenetics
Elsevier Science
110
1
62-4
Yes (verified by ORBi)
International
0165-4608
1873-4456
New York
NY
[en] Aged ; Chromosomes, Human, Pair 2 ; Chromosomes, Human, Pair 3 ; Humans ; Male ; Primary Myelofibrosis/genetics ; Translocation, Genetic
[en] Translocation t(2p;3q) is a rare but recurrent finding in myeloid disorders. We present the first case of primary myelofibrosis with t(2;3)(p21;q26) as the sole chromosomal anomaly. The comparison with the 11 other previously published myeloid-associated t(2p;3q) cases confirms that this nonrandom translocation involves a pluripotent stem cell and is associated with a poor prognosis.
http://hdl.handle.net/2268/10055
also: http://hdl.handle.net/2268/16518

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