Mice; Zebrafish; Transgenesis; Pharmaco-kinetics; Drug safety assessment; Pre-Clinical toxicological studies; Cutomized assays; Generation of transgenics lines; Embryo and sperm cryopreservation; Revitalization of transgenic mouse embryos; Rederivation
Abstract :
[en] In fundamental research, animal models allow to place molecular and cellular observations back into their physiological context.
In applied research, these models still remain a mandatory step to evaluate the efficiency and the toxicity of potential treatments, before going to clinical trials.
Mouse and Zebrafish (Danio rerio) are two very interesting models because of a short live cycle and a high prolificacy. They require a limited space. Their genome is well known and shows a high homology with the human. Many tools are available to produce transgenic mice or zebrafishes. Many tests are validated using both these species.
Drion, Pierre ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques > GIGA-R:Méth. expér.des anim. de labo et éth. en expér. anim.
Language :
English
Title :
GIGA ANIMAL CARE : Mice & Zebrafish Animal Facility and Transgenesis
Publication date :
27 January 2014
Event name :
GIGA Day 2014
Event organizer :
Giga ULg
Event place :
Liège, Belgium
Event date :
january 27 2014
By request :
Yes
Funders :
FEDER - Fonds Européen de Développement Régional [BE] Région wallonne [BE]
