Reference : Suitability of tandem-in-time mass spectrometry for polybrominated diphenylether meas...
Scientific journals : Article
Physical, chemical, mathematical & earth Sciences : Chemistry
Life sciences : Biochemistry, biophysics & molecular biology
http://hdl.handle.net/2268/16410
Suitability of tandem-in-time mass spectrometry for polybrominated diphenylether measurement in fish and shellfish samples: Comparison with high resolution mass spectrometry
English
Pirard, Catherine [Université de Liège - ULG > > > >]
De Pauw, Edwin mailto [Université de Liège - ULg > > Chimie physique, spectrométrie de masse >]
Focant, Jean-François mailto [Université de Liège - ULg > Département de chimie (sciences) > Chimie analytique > >]
May-2006
Journal of Chromatography. A
Elsevier Science Bv
1115
1-2
125-132
Yes (verified by ORBi)
International
0021-9673
Amsterdam
[en] PBDEs ; sample preparation ; EI-MS/MS ; QISTMS ; EI-HRMS ; fish
[en] The first part of the present study focused on the development of an alternative automated sample preparation method for the measurement of selected polybrominated diphenyl ethers (PBDEs) in fish and shellfish. A previously developed automated method has been further optimized and simplified to decrease blank levels and cost. Sorbent and solvent quantities have been significantly reduced without altering extract quality. The second part of the study consisted of comparing tandem-in-time quadrupole ion storage mass spectrometry (QISTMS/MS) to high resolution mass spectrometry (HRMS) for the isotope dilution (ID) measurement step after gas chromatography (GC) separation. Both mass spectrometric methods performed similarly in terms of accuracy but better precision was observed for HRMS. Although better sensitivity can be attained with the high resolution sector instrument, method limits of quantification (mLOQs) were very similar for both approaches as they were dependent on the procedural blanks levels. The mLOQ values ranged between 0.04 and 3.56 ng/g fat, depending on the congener. They allowed the unambiguous identification and quantification of all target analytes, except for BDE-183, in most considered fish extracts. An analytical procedure based on rapid automated sample preparation and QISTMS/MS appeared to be suitable for the measurement of PBDEs in fish and shellfish speciment under quality assurance/quality control (QA/QC) criteria. (c) 2006 Elsevier B.V. All rights reserved.
Centre Interfacultaire d'Analyse des Résidus en Traces - CART
http://hdl.handle.net/2268/16410
10.1016/j.chroma.2006.02.074

File(s) associated to this reference

Fulltext file(s):

FileCommentaryVersionSizeAccess
Restricted access
10.1016j.chroma.2006.02.074.pdfPublisher postprint434.42 kBRequest copy

Bookmark and Share SFX Query

All documents in ORBi are protected by a user license.