Article (Scientific journals)
Utilisation de la metformine chez le patient diabetique cardiaque: balance benefices-risques.
Scheen, André; Paquot, Nicolas
2013In Revue Médicale Suisse, 9 (395), p. 1527-33
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Keywords :
Diabetes Mellitus, Type 2/complications/drug therapy; Heart Diseases/complications; Humans; Hypoglycemic Agents/therapeutic use; Metformin/therapeutic use; Risk Assessment
Abstract :
[en] Metformin is unanimously considered as the first-line glucose-lowering agent in type 2 diabetes. Theoretically, however, it cannot be prescribed in a large proportion of patients because of the presence of numerous contraindications corresponding to situations that may increase the risk of lactic acidosis. Recent data suggest that type 2 diabetes patients who are considered as being "at risk" because of the presence of cardiac disease still take benefit from metformin therapy, with a reduction of morbidity and mortality compared with other glucose-lowering agents. The present review analyzes the benefit-risk balance of metformin therapy in special populations, namely patients with stable coronary artery disease, acute coronary syndrome or myocardial infarction, or congestive heart failure.
Disciplines :
Pharmacy, pharmacology & toxicology
Endocrinology, metabolism & nutrition
Author, co-author :
Scheen, André  ;  Université de Liège - ULiège > Département des sciences cliniques > Diabétologie, nutrition et maladie métaboliques
Paquot, Nicolas ;  Université de Liège - ULiège > Département des sciences de la santé publique > Nutrition
Language :
French
Title :
Utilisation de la metformine chez le patient diabetique cardiaque: balance benefices-risques.
Alternative titles :
[en] Use of metformin in diabetic patients with cardiac disease: benefit-risk balance
Publication date :
2013
Journal title :
Revue Médicale Suisse
ISSN :
1660-9379
Publisher :
Medecine et Hygiène, Switzerland
Volume :
9
Issue :
395
Pages :
1527-33
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 13 January 2014

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