Article (Scientific journals)
Does comfort therapy during controlled donation after circulatory death shorten the life of potential donors?
LEDOUX, Didier; DELBOUILLE, Marie-Hélène; DE ROOVER, Arnaud et al.
2014In Clinical Transplantation, 28 (1), p. 47-51
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Keywords :
end-of-life; ethics; non-heart beating donors; organ donation; policy; transplantation; organ transplantation
Abstract :
[en] INTRODUCTION: Controlled donation after circulatory death (DCD) remains ethically controversial. The authors developed a controlled DCD protocol in which comfort therapy is regularly used. The aim of this study was to determine whether this policy shortens the DCD donors' life. METHODS: The authors retrospectively analyzed prospectively collected data on patients proposed for DCD at the University Hospital of Liege, Belgium, over a 56-month period. The survival duration of these patients, defined as duration between the time of proposal for DCD and the time of circulatory arrest, was compared between patients who actually donated organs and those who did not. RESULTS: About 128 patients were considered for controlled DCD and 54 (43%) became donors. Among the 74 non-donor patients, 34 (46%) objected to organ donation, 38 patients (51%) were denied by the transplant team for various medical reasons, and two potential DCD donors did not undergo procurement due to logistical and organizational reasons. The survival durations were similar in the DCD donor and non-donor groups. No non-donor patient survived. CONCLUSIONS: Survival of DCD donors is not shortened when compared with non-donor patients. These data support the ethical and respectful approach to potential DCD donors in the authors' center, including regular comfort therapy.
Disciplines :
Surgery
Anesthesia & intensive care
Author, co-author :
LEDOUX, Didier  ;  Centre Hospitalier Universitaire de Liège - CHU > Soins intensifs
DELBOUILLE, Marie-Hélène ;  Centre Hospitalier Universitaire de Liège - CHU > Chirurgie abdominale- endocrinienne et de transplantation
DE ROOVER, Arnaud ;  Centre Hospitalier Universitaire de Liège - CHU > Chirurgie abdominale- endocrinienne et de transplantation
LAMBERMONT, Bernard  ;  Centre Hospitalier Universitaire de Liège - CHU > Frais communs médecine
Meurisse, Michel ;  Université de Liège - ULiège > Département des sciences cliniques > Chirurgicale abdominale
DAMAS, Pierre ;  Centre Hospitalier Universitaire de Liège - CHU > Soins intensifs
JORIS, Jean ;  Centre Hospitalier Universitaire de Liège - CHU > Anesthésie et réanimation
DETRY, Olivier  ;  Centre Hospitalier Universitaire de Liège - CHU > Chirurgie abdominale- endocrinienne et de transplantation
Language :
English
Title :
Does comfort therapy during controlled donation after circulatory death shorten the life of potential donors?
Publication date :
January 2014
Journal title :
Clinical Transplantation
ISSN :
0902-0063
eISSN :
1399-0012
Publisher :
Blackwell, Oxford, United Kingdom
Volume :
28
Issue :
1
Pages :
47-51
Peer reviewed :
Peer Reviewed verified by ORBi
Commentary :
(c) 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
Available on ORBi :
since 23 November 2013

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