Article (Scientific journals)
Anti-PSMA antibody-coupled gold nanorods detection by optical and electron microscopies
Schol, Daureen; Fléron, Maximilien; Greisch, Jean françois et al.
2013In Micron, (50), p. 68-74
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Keywords :
gold nanorods; prostate cancer; optoacoustic
Abstract :
[en] While cancer is one of the greatest challenges to public health care, prostate cancer was chosen as cancer model to develop a more accurate imaging assessment than those currently available. Indeed, an efficient imaging technique which considerably improves the sensitivity and specificity of the diagnostic and predicting the cancer behavior would be extremely valuable. The concept of optoacoustic imaging using home-made functionalized gold nanoparticles coupled to an antibody targeting PSMA (prostate specific membrane antigen) was evaluated on different cancer cell lines to demonstrate the specificity of the designed platform.
Research center :
CART - Centre Interfacultaire d'Analyse des Résidus en Traces - ULiège
Giga-Systems Biology and Chemical Biology - ULiège
Disciplines :
Chemistry
Life sciences: Multidisciplinary, general & others
Author, co-author :
Schol, Daureen ;  Université de Liège - ULiège > Form. doct. sc. (chimie - Bologne)
Fléron, Maximilien ;  Université de Liège - ULiège > Doct. sc. bioméd. & pharma. (Bologne)
Greisch, Jean françois;  Institute of Nanotechnology, Karlsruhe Institute of Technology, Karlsruhe, Germany
Jaeger, M;  Institute of Applied Physics, University of Bern, Bern, Switzerland
Frenz, Martin;  Institute of Applied Physics, University of Bern, Bern, Switzerland
De Pauw, Edwin  ;  Université de Liège - ULiège > Département de chimie (sciences) > GIGA-R : Laboratoire de spectrométrie de masse (L.S.M.)
De Pauw-Gillet, Marie-Claire ;  Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Histologie - Cytologie
Language :
English
Title :
Anti-PSMA antibody-coupled gold nanorods detection by optical and electron microscopies
Publication date :
2013
Journal title :
Micron
ISSN :
0968-4328
eISSN :
1878-4291
Publisher :
Pergamon Press - An Imprint of Elsevier Science
Issue :
50
Pages :
68-74
Peer reviewed :
Peer Reviewed verified by ORBi
Name of the research project :
Development of a new integrated biosensor system for an accurate diagnosis of prostate cancer using optoacoustic detection
Funders :
DG RDT - Commission Européenne. Direction Générale de la Recherche et de l'Innovation [BE]
FRIA - Fonds pour la Formation à la Recherche dans l'Industrie et dans l'Agriculture [BE]
Commentary :
FP6 N° NMP4-CT-2005-016880 ADONIS
Available on ORBi :
since 02 September 2013

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