Article (Scientific journals)
Les troubles du contrôle des impulsions associés au traitement dopaminergique substitutif antiparkinsonien
DEPIERREUX, Frédérique; CREMERS, Julien; SKAWINIAK, Eva et al.
2013In Revue Médicale de Liège, 68 (mai-juin), p. 221-225
Peer reviewed
 

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Keywords :
Impulse control behaviour; Parkinson's disease; Dopaminergic therapy
Abstract :
[en] Summary : In some patients, impulse control behaviours can be triggered by dopaminergic replacement therapy, particularly dopamine agonist drugs: hobbyism, punding (stereotyped behaviours), compulsive buying, binge eating disorder, pathological gamgling, hypersexuality, hedonistic homeostatic dysregulation syndrome ... The pathogenesis of these behaviours is not well understood, but likely involves aberrant changes in the dopaminergic pathways that mediate motivation i.e., a dopaminergic “overdose” in meso-cortico-limbic circuits. An early diagnosis is difficult, but mandatory to prevent the occurrence of devastating familial, marital, professional, socio-economic, medical and medico-legal consequences. Their management is not yet well standardized. Patients and caregivers should be warned about impulse control behaviours before starting dopamine agonists and monitoring for such behaviours while on therapy is requested.
Research center :
GIGA CRC (Cyclotron Research Center) In vivo Imaging-Aging & Memory - ULiège
Disciplines :
Neurology
Author, co-author :
DEPIERREUX, Frédérique  ;  Centre Hospitalier Universitaire de Liège - CHU > Neurologie Sart Tilman
CREMERS, Julien ;  Centre Hospitalier Universitaire de Liège - CHU > Neurologie Sart Tilman
SKAWINIAK, Eva ;  Centre Hospitalier Universitaire de Liège - CHU > Neurologie Sart Tilman
Parmentier, Eric  ;  Université de Liège - ULiège > 1re an. master compl. neurol.
DELVAUX, Valérie ;  Centre Hospitalier Universitaire de Liège - CHU > Neurologie Sart Tilman
GARRAUX, Gaëtan  ;  Centre Hospitalier Universitaire de Liège - CHU > Neurologie Sart Tilman
Language :
French
Title :
Les troubles du contrôle des impulsions associés au traitement dopaminergique substitutif antiparkinsonien
Alternative titles :
[en] Impulse control behaviours associated with antiparkinsonian medications
Publication date :
May 2013
Journal title :
Revue Médicale de Liège
ISSN :
0370-629X
eISSN :
2566-1566
Publisher :
Université de Liège. Revue Médicale de Liège, Liège, Belgium
Special issue title :
Toxicomanies, addictions et dépendances (2013)
Volume :
68
Issue :
mai-juin
Pages :
221-225
Peer reviewed :
Peer reviewed
Additional URL :
Available on ORBi :
since 14 August 2013

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