Article (Scientific journals)
Quality of life in sarcopenia and frailty
Rizzoli, René; Reginster, Jean-Yves; Arnal, Jean-François et al.
2013In Calcified Tissue International, 93, p. 101-120
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Keywords :
Age; Aging; Muscle weakness; Quality of life; Malnutrition
Abstract :
[en] The reduced muscle mass and impaired muscle performance that define sarcopenia in older individuals are associated with increased risk of physical limitation and a variety of chronic diseases. They may also contribute to clinical frailty. A gradual erosion of quality of life (QoL) has been evidenced in these individuals, although much of this research has been done using generic QoL instruments, particularly the SF-36, which may not be ideal in older populations with significant comorbidities. This review and report of an expert meeting presents the current definitions of these geriatric syndromes (sarcopenia and frailty). It then briefly summarizes QoL concepts and specificities in older populations and examines the relevant domains of QoL and what is known concerning QoL decline with these conditions. It calls for a clearer definition of the construct of disability, argues that a disease-specific QoL instrumentfor sarcopenia/frailty would be an asset for future research, and discusses whether there are available and validated components that could be used to this end and whether the psychometric properties of these instruments are sufficiently tested. It calls also for an approach using utility weighting to provide some cost estimates and suggests that a time trade-off study could be appropriate.
Disciplines :
Geriatrics
Public health, health care sciences & services
Author, co-author :
Rizzoli, René
Reginster, Jean-Yves  ;  Université de Liège - ULiège > Département des sciences de la santé publique > Santé publique, Epidémiologie et Economie de la santé
Arnal, Jean-François
Bautmans, Ivan
Beaudart, Charlotte ;  Université de Liège - ULiège > Département des sciences de la santé publique > Santé publique, Epidémiologie et Economie de la santé
Bischoff-Ferrari, Heike
Biver, Emmanuel
Boonen, Steven
Brandi, Maria-Louisa
Chines, Arkadi
Cooper, Cyrus
Epstein, Sol
Fielding, Roger A
Goodpaster, Bret
Kanis, John A
Kaufman, Jean-Marc
Laslop, Andrea
Malafarina, Vincenzo
Rodriguez Mañas, Leocadio
Mitlak, Bruce H
Oreffo, Richard O
Petermans, Jean ;  Université de Liège - ULiège > Département des sciences cliniques > Gériatrie
Reid, Kieran
Rolland, Yves
Sayer, Avan Aihie
Tsouderos, Yannis
Visser, Marjolein
Bruyère, Olivier  ;  Université de Liège - ULiège > Département des sciences de la santé publique > Santé publique, Epidémiologie et Economie de la santé
More authors (18 more) Less
Language :
English
Title :
Quality of life in sarcopenia and frailty
Publication date :
July 2013
Journal title :
Calcified Tissue International
ISSN :
0171-967X
eISSN :
1432-0827
Publisher :
Springer Verlag, New York, United States - New York
Volume :
93
Pages :
101-120
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 08 July 2013

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