Reference : Cold-adapted enzymes from marine antarctic microorganisms
Scientific journals : Article
Life sciences : Biochemistry, biophysics & molecular biology
Cold-adapted enzymes from marine antarctic microorganisms
Marx, J. C. [> > > >]
Collins, T. [> > > >]
D'Amico, Salvino [Université de Liège - ULg > > GIGA-Research >]
Feller, Georges mailto [Université de Liège - ULg > Département des sciences de la vie > Labo de biochimie >]
Gerday, Charles mailto [Université de Liège - ULg > Services généraux (Faculté des sciences) > Relations académiques et scientifiques (Sciences) >]
Marine Biotechnology
3, May-Jun
Yes (verified by ORBi)
New York
[en] Antarctic ; biotechnology ; cold adaptation ; psychrophiles
[en] The Antarctic marine environment is characterized by challenging conditions for the survival of native microorganisms. Indeed, next to the temperature effect represented by the Arrhenius law, the viscosity of the medium, which is also significantly enhanced by low temperatures, contributes to slow down reaction rates. This review analyses the different challenges and focuses on a key element of life at low temperatures: cold-adapted enzymes. The molecular characteristics of these enzymes are discussed as well as the adaptation strategies which can be inferred from the comparison of their properties and three-dimensional structures with those of their mesophilic counterparts. As these enzymes display a high specific activity at low and moderate temperatures associated with a relatively high thermosensitivity, the interest in these properties is discussed with regard to their current and possible applications in biotechnology.

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