Article (Scientific journals)
Childhood Herpes Zoster-Triggered Guttate Psoriasis
FAILLA, Valérie; NIKKELS, Nazli; SABATIELLO, Murielle et al.
2012In Open Dermatology Journal, 6, p. 9-12
Peer reviewed
 

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Keywords :
Herpes zoster; Varicella zoster; psoriasis; child
Abstract :
[en] Psoriasis is commonly triggered or exacerbated by various stress factors, certain drugs, or streptococcal throat infections. Viral infections such as HIV, CMV, chikungunya, or herpes simplex virus are very uncommon triggers for psoriasis. Cases of varicella-triggered psoriasis are exceptional. A 7-year-old boy with a previous history of guttate psoriasis presented with generalized acute guttate psoriasis shortly after an extensive herpes zoster infection affecting the first and second left lumbar dermatomes. INF-alpha and granulocyte monocyte colony stimulating factor influence peripheral monocytes to transform into INF-dendritic cells (DC's), similar to those involved in psoriasis. These INF-DC's express toll-like receptors 7 and 8, which are responsive to viral single stranded RNA. Hence, viral infections and interferon (INF)-alpha may play a role in triggering psoriasis.
Disciplines :
Dermatology
Author, co-author :
FAILLA, Valérie ;  Centre Hospitalier Universitaire de Liège - CHU > Dermatologie
NIKKELS, Nazli ;  Centre Hospitalier Universitaire de Liège - CHU > Dermatologie
SABATIELLO, Murielle ;  Centre Hospitalier Universitaire de Liège - CHU > Dermatologie
DE SCHAETZEN VAN BRIENEN, Virginie ;  Centre Hospitalier Universitaire de Liège - CHU > Dermatologie
NIKKELS, Arjen ;  Centre Hospitalier Universitaire de Liège - CHU > Dermatologie
Language :
English
Title :
Childhood Herpes Zoster-Triggered Guttate Psoriasis
Publication date :
2012
Journal title :
Open Dermatology Journal
eISSN :
1874-3722
Publisher :
Bentham Science Publishers, Bussum, Netherlands
Volume :
6
Pages :
9-12
Peer reviewed :
Peer reviewed
Available on ORBi :
since 30 May 2012

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