Article (Scientific journals)
EORTC-ROG expert opinion: Radiotherapy volume and treatment guidelines for neoadjuvant radiation of adenocarcinomas of the gastroesophageal junction and the stomach
Matzinger, O.; Gerber, E.; Bernstein, Z. et al.
2009In Radiotherapy and Oncology, 92 (2), p. 164-175
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Matzinger et al. - 2009 - EORTC-ROG expert opinion radiotherapy volume and treatment guidelines for neoadjuvant radiation of adenocarcinomas of the gastroesophageal junction and the stomach. - Radiother Oncol.pdf
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Keywords :
Gastric; Gastroesophageal; Guideline; Neoadjuvant; Radiotherapy; Target volume; MEDLINE; Adenocarcinoma; Esophagogastric Junction; Humans; Neoadjuvant Therapy; Practice Guidelines as Topic; Stomach Neoplasms
Abstract :
[en] Purpose: The Gastro-Intestinal Working Party of the EORTC Radiation Oncology Group (GIWP-ROG) developed guidelines for target volume definition in neoadjuvant radiation of adenocarcinomas of the gastroesophageal junction (GEJ) and the stomach. Methods and materials: Guidelines about the definition of the clinical target volume (CTV) are based on a systematic literature review of the location and frequency of local recurrences and lymph node involvement in adenocarcinomas of the GEJ and the stomach. Therefore, MEDLINE was searched up to August 2008. Guidelines concerning prescription, planning and treatment delivery are based on a consensus between the members of the GIWP-ROG. Results: In order to support a curative resection of GEJ and gastric cancer, an individualized preoperative treatment volume based on tumour location has to include the primary tumour and the draining regional lymph nodes area. Therefore we recommend to use the 2nd English Edition of the Japanese Classification of Gastric Carcinoma of the Japanese Gastric Cancer Association which developed the concept of assigning tumours of the GEJ and the stomach to anatomically defined sub-sites corresponding respectively to a distinct lymphatic spread pattern. Conclusion: The GIWP-ROG defined guidelines for preoperative irradiation of adenocarcinomas of the GEJ and the stomach to reduce variability in the framework of future clinical trials. © 2009 Elsevier Ireland Ltd. All rights reserved.
Disciplines :
Radiology, nuclear medicine & imaging
Author, co-author :
Matzinger, O.;  EORTC Headquarters, Brussels, Belgium, CHU Vaudois, Department of Radiation Oncology, Lausanne, Switzerland
Gerber, E.
Bernstein, Z.;  Rambam Health Care Campus, Oncology Department, Haifa, Israel
Maingon, P.;  Centre Georges-Francois Leclerc, Department of Radiation Oncology, Dijon, France
Haustermans, K.;  U.Z. Gasthuisberg, Department of Radiation Oncology, Leuven, Belgium
Bosset, J. F.;  CHR de Besancon, Department of Radiation Oncology, Besancon, France
GULYBAN, Akos ;  Centre Hospitalier Universitaire de Liège - CHU > Radiothérapie
Poortmans, P.;  Dr. Bernard Verbeeten Institute, Department of Radiation Oncology, Tilburg, Netherlands
Collette, L.;  EORTC Headquarters, Brussels, Belgium
Kuten, A.;  Rambam Health Care Campus, Oncology Department, Haifa, Israel
Language :
English
Title :
EORTC-ROG expert opinion: Radiotherapy volume and treatment guidelines for neoadjuvant radiation of adenocarcinomas of the gastroesophageal junction and the stomach
Publication date :
2009
Journal title :
Radiotherapy and Oncology
ISSN :
0167-8140
eISSN :
1879-0887
Publisher :
Elsevier Scientific, Limerick, Ireland
Volume :
92
Issue :
2
Pages :
164-175
Peer reviewed :
Peer Reviewed verified by ORBi
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