Article (Scientific journals)
beta-Catenin and ZO-1: Shuttle molecules involved in tumor invasion-associated epithelial-mesenchymal transition processes
Polette, M.; Mestdagt, Mélanie; Bindels, Sandrine et al.
2007In Cells, Tissues, Organs, 185 (1-3), p. 61-65
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Keywords :
beta-catenin; ZO-1; vimentin; matrix metalloproteinase; epithelial-mesenchymal transition
Abstract :
[en] The cytoplasmic/nuclear relocalization of beta-catenin and ZO-1 from the adherens and tight junctions are common processes of the epithelial-mesenchymal transition (EMT) associated with tumor invasion. Data are now accumulating to demonstrate that these molecules, which shuttle between the plasma membrane and the nucleus or the cytosol, are involved in signaling pathways, and contribute to the regulation of genes such as vimentin or matrix metalloproteinase-14 which are turned on during EMT. Copyright (c) 2007 S. Karger AG, Basel.
Disciplines :
Anatomy (cytology, histology, embryology...) & physiology
Biochemistry, biophysics & molecular biology
Author, co-author :
Polette, M.
Mestdagt, Mélanie 
Bindels, Sandrine ;  Université de Liège - ULiège > Département des sciences cliniques > Labo de biologie des tumeurs et du développement
Nawrocki-Raby, B.
Hunziker, W.
Foidart, Jean-Michel ;  Université de Liège - ULiège > Département des sciences cliniques > Gynécologie - Obstétrique
Birembaut, P.
Gilles, Christine ;  Université de Liège - ULiège > Département des sciences cliniques > Labo de biologie des tumeurs et du développement
Language :
English
Title :
beta-Catenin and ZO-1: Shuttle molecules involved in tumor invasion-associated epithelial-mesenchymal transition processes
Publication date :
2007
Journal title :
Cells, Tissues, Organs
ISSN :
1422-6405
eISSN :
1422-6421
Publisher :
Karger, Basel, Switzerland
Volume :
185
Issue :
1-3
Pages :
61-65
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 22 June 2009

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