ORBi: Van Galen Gaby - The Composition of the Inflammatory Infiltrate in Three Cases of Polyneuritis Equi

Reference : The Composition of the Inflammatory Infiltrate in Three Cases of Polyneuritis Equi


	Document type :	Scientific journals : Article
	Discipline(s) :	Life sciences : Veterinary medicine & animal health
	To cite this reference:	http://hdl.handle.net/2268/14899

Title :	The Composition of the Inflammatory Infiltrate in Three Cases of Polyneuritis Equi
Language :	English
Author, co-author :	Van Galen, Gaby [Université de Liège - ULg > Département clinique des animaux de compagnie et des équidés > Département clinique des animaux de compagnie et des équidés >]
	Cassart, Dominique [Université de Liège - ULg > Département de morphologie et pathologie > Département de morphologie et pathologie >]
	Sandersen, Charlotte [Université de Liège - ULg > Département clinique des animaux de compagnie et des équidés > Département clinique des animaux de compagnie et des équidés >]
	Delguste, Catherine [Université de Liège - ULg > Département de sciences fonctionnelles > Pharmacologie, pharmacothérapie et toxicologie >]
	Nollet, Heidi [University of Ghent > Vakgroep Interne geneeskunde en klinische biologie van de grote huisdieren > > >]
	Amory, Hélène [Université de Liège - ULg > Département clinique des animaux de compagnie et des équidés > Médecine interne des équidés >]
	Ducatelle, Rick [University of Ghent > Vakgroep Pathologie, bacteriologie en pluimveeziekten > > >]
Publication date :	Mar-2008
Journal title :	Equine Veterinary Journal
Volume :	40
Issue/season :	2
Pages :	185-8
Peer reviewed :	Yes (verified by ORBi)
Audience :	International
ISSN :	0425-1644
Abstract :	[en] Polyneuritis equi (PNE) is a rare neurological disease in the horse. Because of the suspicion in PNE of a T-lymphocyte mediated immune response against the myelin, the objective of this study was to determine the composition of the inflammatory infiltrate in the involved nerves of 3 horses with PNE, studied retrospectively. T-lymphocytes were demonstrated in the lesions, which suggests a T-lymphocyte mediated immune response against myelin. In addition, the presence of B-lymphocytes indicated a local production of antibodies. More research, involving a prospective study, is needed to determine whether the T-lymphocytes are cytotoxic or T-helper lymphocytes.
Target :	Researchers ; Professionals
Permalink :	http://hdl.handle.net/2268/14899
DOI :	10.2746/042516408X276933

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