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Enzymatic synthesis, surface and lipid interaction properties of novel rhamnolipids
Nott, Katherine; Richard, Gaetan; Deleu, Magali
2013104th AOCS Annual Meeting & Expo 2013
Peer reviewed
 

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Abstract :
[en] Amongst glycolipidid biosurfactants, rhamnolipids have drawn particular attention as they have several interesting biological properties such as antimicrobial, antiphytoviral, zoosporicidal and plant defense elicitor activities [1-3]. It is generally recognised that these activities must be linked to the interaction of these molecules with constituents of biological membranes [4] but the detailed mechanism is far from being fully understood. The objective of this work is double. First, it aims to investigate a new strategy of synthesis for the production of novel rhamnolipids [5] that could exhibit properties as promising for industrial and environmental applications as their natural counterparts while avoiding the use of the pathogenic Pseudomonas aeruginosa for their production. Secondly, their basic surface properties (critical aggregation concentration, surface tension at CAC and interfacial behaviour of their monolayer) and their interaction with model membranes are investigated in relation with their structure in order to give insight about the mechanism of their biological actions. [1] Vatsa P. et al. Int. J. Mol. Sci. 2010;11:5095. [2] Varnier A-L. et al. Plant, Cell Environ. 2009;32:178. [3] Lang S. et al. Appl. Microbiol. Biotechn. 1999;51:22. [4] Aranda F.J. et al. Langmuir. 2007;23:2700. [5] Nott K. et al. Process Biochemistry, http://dx.doi.org/10.1016/j.procbio.2012.11.019
Disciplines :
Chemistry
Author, co-author :
Nott, Katherine ;  Université de Liège - ULiège > Chimie et bio-industries > Chimie biologique industrielle
Richard, Gaetan ;  Université de Liège - ULiège > Chimie et bio-industries > Chimie biologique industrielle
Deleu, Magali  ;  Université de Liège - ULiège > Chimie et bio-industries > Chimie biologique industrielle
Language :
English
Title :
Enzymatic synthesis, surface and lipid interaction properties of novel rhamnolipids
Publication date :
2013
Event name :
104th AOCS Annual Meeting & Expo 2013
Event place :
Montreal, Canada
Event date :
28 avril 2013 au 1 mai 2013
By request :
Yes
Audience :
International
Peer reviewed :
Peer reviewed
Name of the research project :
ARC superzym
Available on ORBi :
since 15 May 2013

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