Poster (Scientific congresses and symposiums)
Influence of the mode of walk on walking speed in multiple sclerosis: are you walking comfortably?
PHAN BA, Remy; DELRUE, Gaël; Pierard, Sébastien et al.
2013Twenty-third meeting of the European Neurological Society
 

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Keywords :
walking speed; multiple sclerosis
Abstract :
[en] Introduction : Walking speed (WS) is the most frequent gait variable taken into account when measuring gait dysfunction in neurological diseases. Influences of the mode of walk instructed to the subject, i.e. « as fast as possible » (AFAP) or « at a comfortable pace » (PrP) have not been well characterized in multiple sclerosis (MS). Objectives : to compare those 2 mode of walk in a population of persons with MS (pMS) and healthy volunteers (HV). Methods: WS was measured with a new automated device along a 25 foot distance (T25FW) as part of a multimodal evaluation of gait in an MS ambulatory department. Results: Baseline demographics between HV and pMS were comparable. Our first results demonstrate that (i) WS is obviously significantly higher in AFAP than in PrP both for pMS and HV (p < 0.001 for all comparisons) and (ii) the relative difference between AFAP and PrP WS is significantly higher in HV than in pMS (p < 0.001). The AFAP-PrP WS correlation is higher in pMS (r = 0.87, p < 0.001) than in HV (r = 0.51, p < 0.001). Finally, the relative difference between AFAP and PrP WS is significantly and negatively correlated with the PrP WS in HV (r = -0.41, p < 0.001) and pMS with mild to moderate disability (EDSS 0-3.5, r = -0.49, p < 0.01) but not in pMS with high disability (EDSS 4-5.5, r = 0.008). Conclusions : these results suggests that heatlhy subjects have access to a higher range of PrP WS than pMS and questions the regulation of PrP WS that might be under psychological or behavioural influences. The demonstration of a lower PrP-AFAP difference in MS suggests that pMS are either adopting a natural WS closer to their maximum WS, or alternatively that they can’t reach their maximum WS because of neurological impairments. Our results also emphasize the importance of the instructed mode of walk in the quantification of gait disorders both for routine clinical practice and clinical trials.
Disciplines :
Neurology
Author, co-author :
PHAN BA, Remy ;  Centre Hospitalier Universitaire de Liège - CHU > Neurologie Sart Tilman
DELRUE, Gaël ;  Centre Hospitalier Universitaire de Liège - CHU > Neurologie Sart Tilman
Pierard, Sébastien ;  Université de Liège - ULiège > Dép. d'électric., électron. et informat. (Inst.Montefiore) > Dép. d'électric., électron. et informat. (Inst.Montefiore)
LOMMERS, Emilie  ;  Centre Hospitalier Universitaire de Liège - CHU > Neurologie Sart Tilman
CALAY, Philippe ;  Centre Hospitalier Universitaire de Liège - CHU > Neurologie Sart Tilman
Van Droogenbroeck, Marc  ;  Université de Liège - ULiège > Dép. d'électric., électron. et informat. (Inst.Montefiore) > Télécommunications
DELVAUX, Valérie ;  Centre Hospitalier Universitaire de Liège - CHU > Neurologie Sart Tilman
Language :
English
Title :
Influence of the mode of walk on walking speed in multiple sclerosis: are you walking comfortably?
Publication date :
10 June 2013
Event name :
Twenty-third meeting of the European Neurological Society
Event organizer :
European Neurological Society
Event place :
Barcelona, Spain
Event date :
08-11 June 2013
Audience :
International
Available on ORBi :
since 05 March 2013

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