[en] Cerebral blood flow was estimated using positron emission tomography and H2O15 infusions in 12 volunteers while they were trained on the probabilistic serial reaction time task developed by Jimenez, Mender, and Cleeremans (1996). Participants' reaction rimes to predictable and nonpredictable stimuli showed increasing sensitivity to the: probabilistic constraints set by previous elements of the sequence. Analysis by statistical parametric mapping showed a significant interaction between participants' performance and time effect in the left inferior frontal cortex. Our results provide the first evidence of this cerebral area being involved in the processing of contextual information in a probabilistic sequence learning task.
Disciplines :
Neurosciences & behavior
Author, co-author :
Peigneux, Philippe ; Université de Liège - ULiège > Département des sciences cognitives > Département des sciences cognitives
Maquet, Pierre ; Université de Liège - ULiège > Centre de recherches du cyclotron
Van der Linden, Martial ; Université de Liège - ULiège > Département des sciences cognitives > Psychopathologie cognitive
Meulemans, Thierry ; Université de Liège - ULiège > Département des sciences cognitives > Neuropsychologie
Degueldre, Christian ; Université de Liège - ULiège > Centre de recherches du cyclotron
Delfiore, Guy
Luxen, André ; Université de Liège - ULiège > Département de chimie (sciences) > Chimie organique de synthèse - Centre de recherches du cyclotron
Cleeremans, Axel
Franck, Georges ; Université de Liège - ULiège > Relations académiques et scientifiques (Médecine)
Language :
English
Title :
Left inferior frontal cortex is involved in probabilistic serial reaction time learning
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