Article (Scientific journals)
Giant Condyloma of the Cervix: An Uncommon Entity Associated With Low-risk Human Papilloma Virus Infection.
Parra-Herran, Carlos; Herfs, Michael; Doria, Manuel et al.
2013In American Journal of Surgical Pathology, 37 (2), p. 300-4
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Abstract :
[en] "Giant Condylomas" of the cervix are very uncommon, and have not been fully characterized in the English literature. We report 4 cases of cervical giant condyloma seen in our practice. Patients were predominantly young and presented with a cervical lesion producing bleeding or a mass effect. Biopsy/excision revealed a uniformly bland, exophytic squamous epithelial proliferation with viral cytopathic changes and absence of stromal invasion. Human papilloma virus types 6 and 11 were detected in all cases. Follow-up was uneventful without recurrence or spread. Giant condylomas of the cervix as defined in this report signify a benign albeit extensive variant of low-risk human papilloma virus infection. This term is proposed as a specific descriptor for such lesions and should be considered in the setting of any large well-differentiated exophytic cervical squamous lesion in young or immunosuppressed women. The term "giant condyloma of Buschke and Loewenstein" should be discontinued given the lack of specificity.
Disciplines :
Oncology
Author, co-author :
Parra-Herran, Carlos
Herfs, Michael ;  Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Anatomie et cytologie pathologiques
Doria, Manuel
Crum, Christopher P.
Nucci, Marisa R.
Language :
English
Title :
Giant Condyloma of the Cervix: An Uncommon Entity Associated With Low-risk Human Papilloma Virus Infection.
Publication date :
2013
Journal title :
American Journal of Surgical Pathology
ISSN :
0147-5185
eISSN :
1532-0979
Publisher :
Lippincott Williams & Wilkins, United States - New York
Volume :
37
Issue :
2
Pages :
300-4
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 28 January 2013

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